Circular RNAs: Splicing's enigma variations

Matthias W. Hentze; Thomas Preiss

doi:10.1038/emboj.2013.53

Circular RNAs: Splicing's enigma variations

Matthias W. Hentze, Thomas Preiss^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

405 Citations (Scopus)

Abstract

Circular (circ)RNAs are to transcriptomics what the famous hidden musical theme is to Elgar's Enigma Variations: woven into the entire composition but not unambiguously identified or understood by scholars to this day. Now, two studies (Hansen et al, 2013; Memczak et al, 2013) have made substantial progress in both, identifying thousands of circRNAs and beginning to crack the enigma of their cellular function, by demonstrating that the circRNAs CiRS-7/CDR1as and SRY function as natural and highly stable sponges for specific microRNAs.

Original language	English
Pages (from-to)	923-925
Number of pages	3
Journal	EMBO Journal
Volume	32
Issue number	7
DOIs	https://doi.org/10.1038/emboj.2013.53
Publication status	Published - 3 Apr 2013

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10.1038/emboj.2013.53

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Circular RNAs: Splicing's enigma variations

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