Cis-1,2-Dihydrocatechols in chemical synthesis: First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source

Martin G. Banwell; Simon Blakey; Gwion Harfoot; Robert W. Longmore

doi:10.1071/C98157

Cis-1,2-Dihydrocatechols in chemical synthesis: First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source

Martin G. Banwell^*, Simon Blakey, Gwion Harfoot, Robert W. Longmore

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

16 Citations (Scopus)

Abstract

The cis-1,2-dihydrocatechol (2), which is obtained in enantiopure form by microbial oxidation of chlorobenzene, has been converted, via 3,5-O-benzylidene-L-gulono-1,4-lactone (8), into L-ascorbic acid (1).

Original language	English
Pages (from-to)	137-142
Number of pages	6
Journal	Australian Journal of Chemistry
Volume	52
Issue number	2
DOIs	https://doi.org/10.1071/C98157
Publication status	Published - 1999

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title = "Cis-1,2-Dihydrocatechols in chemical synthesis: First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source",

abstract = "The cis-1,2-dihydrocatechol (2), which is obtained in enantiopure form by microbial oxidation of chlorobenzene, has been converted, via 3,5-O-benzylidene-L-gulono-1,4-lactone (8), into L-ascorbic acid (1).",

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year = "1999",

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journal = "Australian Journal of Chemistry",

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T2 - First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source

AU - Banwell, Martin G.

AU - Blakey, Simon

AU - Harfoot, Gwion

AU - Longmore, Robert W.

PY - 1999

Y1 - 1999

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AB - The cis-1,2-dihydrocatechol (2), which is obtained in enantiopure form by microbial oxidation of chlorobenzene, has been converted, via 3,5-O-benzylidene-L-gulono-1,4-lactone (8), into L-ascorbic acid (1).

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U2 - 10.1071/C98157

DO - 10.1071/C98157

M3 - Article

SN - 0004-9425

VL - 52

SP - 137

EP - 142

JO - Australian Journal of Chemistry

JF - Australian Journal of Chemistry

IS - 2

ER -

Cis-1,2-Dihydrocatechols in chemical synthesis: First synthesis of L-ascorbic acid (vitamin C) from a non-carbohydrate source

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