Cisplatin: Polymorphism and structural insights into an important chemotherapeutic drug

Valeska P. Ting; Marc Schmidtmann; Chick C. Wilson; Mark T. Weller

doi:10.1002/anie.201003185

Cisplatin: Polymorphism and structural insights into an important chemotherapeutic drug

Valeska P. Ting, Marc Schmidtmann, Chick C. Wilson, Mark T. Weller

Research output: Contribution to journal › Article › peer-review

36 Citations (Scopus)

Abstract

The changing face of cisplatin: The complete crystal structures, including the details of extensive intermolecular hydrogen bonding in two enantiotropic polymorphs of the chemotherapeutic drug cisplatin, have been elucidated. A massive thermal hysteresis effect exists between the two polymorphs, α and β, that are active at ambient temperatures.

Original language	English
Pages (from-to)	9408-9411
Number of pages	4
Journal	Angewandte Chemie - International Edition
Volume	49
Issue number	49
DOIs	https://doi.org/10.1002/anie.201003185
Publication status	Published - 3 Dec 2010
Externally published	Yes

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10.1002/anie.201003185

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title = "Cisplatin: Polymorphism and structural insights into an important chemotherapeutic drug",

abstract = "The changing face of cisplatin: The complete crystal structures, including the details of extensive intermolecular hydrogen bonding in two enantiotropic polymorphs of the chemotherapeutic drug cisplatin, have been elucidated. A massive thermal hysteresis effect exists between the two polymorphs, α and β, that are active at ambient temperatures.",

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AU - Wilson, Chick C.

AU - Weller, Mark T.

PY - 2010/12/3

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KW - phase transitions

KW - polymorphism

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Cisplatin: Polymorphism and structural insights into an important chemotherapeutic drug

Abstract

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