Clinical Description of a Completed Outbreak of SARS in Vietnam February-May 2003

Hoang Thu Vu; Katrin C. Leitmeyer; Dang Ha Le; Megge J. Miller; Quang Hien Nguyen; Timothy M. Uyeki; Mary G. Reynolds; Jesper Aagesen; Karl G. Nicholson; Quang Huy Vu; Huy Anh Bach; Aileen J. Plant

doi:10.3201/eid1002.030761

Clinical Description of a Completed Outbreak of SARS in Vietnam February-May 2003

Hoang Thu Vu, Katrin C. Leitmeyer, Dang Ha Le, Megge J. Miller, Quang Hien Nguyen, Timothy M. Uyeki, Mary G. Reynolds, Jesper Aagesen, Karl G. Nicholson, Quang Huy Vu, Huy Anh Bach, Aileen J. Plant^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

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Abstract

We investigated the clinical manifestations and course of all probable severe acute respiratory syndrome (SARS) patients in the Vietnam outbreak. Probable SARS cases were defined by using the revised World Health Organization criteria. We systematically reviewed medical records and undertook descriptive statistical analyses. All 62 patients were hospitalized. On admission, the most prominent symptoms were malaise (82.3%) and fever (79.0%). Cough, chest pain, and shortness of breath were present in approximately one quarter of the patients; 79.0% had lymphopenia; 40.3% had thrombocytopenia; 19.4% had leukopenia; and 75.8% showed changes on chest radiograph. Fever developed on the first day of illness onset, and both respiratory symptoms and radiographic changes occurred on day 4. On average, maximal radiographic changes were observed on day 10, and fevers subsided by day 13. Symptoms on admission were nonspecific, although fever, malaise, and lymphopenia were common. The complications of SARS included invasive intubation and ventilation (11.3%) and death (9.7%).

Original language	English
Pages (from-to)	334-338
Number of pages	5
Journal	Emerging Infectious Diseases
Volume	10
Issue number	2
DOIs	https://doi.org/10.3201/eid1002.030761
Publication status	Published - Feb 2004

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title = "Clinical Description of a Completed Outbreak of SARS in Vietnam February-May 2003",

abstract = "We investigated the clinical manifestations and course of all probable severe acute respiratory syndrome (SARS) patients in the Vietnam outbreak. Probable SARS cases were defined by using the revised World Health Organization criteria. We systematically reviewed medical records and undertook descriptive statistical analyses. All 62 patients were hospitalized. On admission, the most prominent symptoms were malaise (82.3%) and fever (79.0%). Cough, chest pain, and shortness of breath were present in approximately one quarter of the patients; 79.0% had lymphopenia; 40.3% had thrombocytopenia; 19.4% had leukopenia; and 75.8% showed changes on chest radiograph. Fever developed on the first day of illness onset, and both respiratory symptoms and radiographic changes occurred on day 4. On average, maximal radiographic changes were observed on day 10, and fevers subsided by day 13. Symptoms on admission were nonspecific, although fever, malaise, and lymphopenia were common. The complications of SARS included invasive intubation and ventilation (11.3%) and death (9.7%).",

author = "Vu, {Hoang Thu} and Leitmeyer, {Katrin C.} and Le, {Dang Ha} and Miller, {Megge J.} and Nguyen, {Quang Hien} and Uyeki, {Timothy M.} and Reynolds, {Mary G.} and Jesper Aagesen and Nicholson, {Karl G.} and Vu, {Quang Huy} and Bach, {Huy Anh} and Plant, {Aileen J.}",

year = "2004",

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doi = "10.3201/eid1002.030761",

language = "English",

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AU - Vu, Hoang Thu

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AU - Nguyen, Quang Hien

AU - Uyeki, Timothy M.

AU - Reynolds, Mary G.

AU - Aagesen, Jesper

AU - Nicholson, Karl G.

AU - Vu, Quang Huy

AU - Bach, Huy Anh

AU - Plant, Aileen J.

PY - 2004/2

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N2 - We investigated the clinical manifestations and course of all probable severe acute respiratory syndrome (SARS) patients in the Vietnam outbreak. Probable SARS cases were defined by using the revised World Health Organization criteria. We systematically reviewed medical records and undertook descriptive statistical analyses. All 62 patients were hospitalized. On admission, the most prominent symptoms were malaise (82.3%) and fever (79.0%). Cough, chest pain, and shortness of breath were present in approximately one quarter of the patients; 79.0% had lymphopenia; 40.3% had thrombocytopenia; 19.4% had leukopenia; and 75.8% showed changes on chest radiograph. Fever developed on the first day of illness onset, and both respiratory symptoms and radiographic changes occurred on day 4. On average, maximal radiographic changes were observed on day 10, and fevers subsided by day 13. Symptoms on admission were nonspecific, although fever, malaise, and lymphopenia were common. The complications of SARS included invasive intubation and ventilation (11.3%) and death (9.7%).

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Clinical Description of a Completed Outbreak of SARS in Vietnam February-May 2003

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