Comparison of the atavistic model of cancer to somatic mutation theory: Phylostratigraphic analyses support the atavistic model

Charles H. Lineweaver; Paul C.W. Davies

doi:10.1142/9789811223495_0012

Comparison of the atavistic model of cancer to somatic mutation theory: Phylostratigraphic analyses support the atavistic model

Charles H. Lineweaver, Paul C.W. Davies

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

9 Citations (Scopus)

Abstract

We review the atavistic model of cancer¹ and compare it with the leading model: Somatic Mutation Theory (SMT). We identify their differences and describe specific predictions of the atavistic model that make it more easily tested than SMT. The increasingly dense phylogenetic tree of all life on Earth has permitted a range of phylostratigraphic analyses which support the atavistic model.

Original language	English
Title of host publication	Physics Of Cancer, The
Subtitle of host publication	Research Advances
Publisher	World Scientific Publishing Co
Pages	243-261
Number of pages	19
ISBN (Electronic)	9789811223495
DOIs	https://doi.org/10.1142/9789811223495_0012
Publication status	Published - 1 Jan 2020

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Comparison of the atavistic model of cancer to somatic mutation theory: Phylostratigraphic analyses support the atavistic model

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