Computational Single-Objective Light-Sheet Microscopy for Imaging Microfluidics

Tienan Xu, Woei Ming Lee*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

Abstract

Existing light-sheet microscopy has limited adoption in microfluidic studies due to physical constraints imposed by the working distance from multiple objective lenses, significant modification of microfluidic chip, or complex imaging setups. We demonstrate single-objective light-sheet microscopy that is fully compatible with microfluidic devices. A key improvement is the real-time volumetric, optically sectioned imaging by oblique light-sheet with a novel computational light-field reconstruction algorithm.

Original languageEnglish
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Place of PublicationSan Diego
PublisherChemical and Biological Microsystems Society
Pages1589-1590
ISBN (Electronic)9781733419031
ISBN (Print)9781713855736
Publication statusPublished - 2021
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States
Duration: 10 Oct 202114 Oct 2021
https://microtasconferences.org/microtas2021/about/conference_info.html

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Abbreviated titleMicroTAS 2021
Country/TerritoryUnited States
CityPalm Springs, Virtual
Period10/10/2114/10/21
OtherFrom October 10-14, 2021, the 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (µTAS 2021) will be held as a hybrid meeting for the first time in our conference's history. The in-person component -- held at the Palm Springs Convention Center in Palm Springs, California, USA -- will be paired with a virtual conference site hosted on-line. In tandem with an on-site program, cutting edge technical solutions and live streaming tools, as well as early creation of community, will allow us to bring microTAS content and connections to attendees anywhere in the world.

After an historic period that highlights the impacts of scientific knowledge and international collaboration (and lack thereof), we see no better time to convene our global scientific community as we push our understanding forward to meet the rising demands of the 21st century.

µTAS 2021 continues an international Conference series that is the premier forum for reporting research results in microfluidics, microfabrication, nanotechnology, integration, materials and surfaces, analysis and synthesis, and detection technologies for the life sciences and chemistry. The Conference offers plenary and invited talks, expansive poster sessions, networking forums, and an array of industry exhibitions, as well as numerous contributed oral and poster presentations selected from submitted abstracts. Owing to the µTAS 2021 hybrid format, each aspect offers in-person and remote attendees the opportunity to share, learn, and engage.
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