TY - JOUR
T1 - Conceptual problems in cardiological Prediction
AU - Gregson, Robert A.M.
PY - 2009/4
Y1 - 2009/4
N2 - The internal dynamics of cardiac activity are complex and can vary significantly over time, individuals may exhibit chaos, singularities, and nonstationarity at various time scales. The heart is one of the most studied psychobiological nonlinear systems, at various levels of mathematical and statistical sophistication. Some of its properties can be associated with morbidity or mortality. Prediction of when activity will terminate without acute clinical intervention is only possible at a statistical level over homogeneous groups of subjects under known conditions. Various consequent problems with data analysis at both individual and group levels are reviewed; the two related inferential issues, from individual dynamics to epidemiology, and from epidemiology to individual treatment issues, are critically examined.
AB - The internal dynamics of cardiac activity are complex and can vary significantly over time, individuals may exhibit chaos, singularities, and nonstationarity at various time scales. The heart is one of the most studied psychobiological nonlinear systems, at various levels of mathematical and statistical sophistication. Some of its properties can be associated with morbidity or mortality. Prediction of when activity will terminate without acute clinical intervention is only possible at a statistical level over homogeneous groups of subjects under known conditions. Various consequent problems with data analysis at both individual and group levels are reviewed; the two related inferential issues, from individual dynamics to epidemiology, and from epidemiology to individual treatment issues, are critically examined.
KW - Cardiac dynamics
KW - Epidemiology
KW - Micro and macro levels
KW - Singularities
KW - System theory
UR - http://www.scopus.com/inward/record.url?scp=66849141997&partnerID=8YFLogxK
M3 - Article
SN - 1090-0578
VL - 13
SP - 209
EP - 223
JO - Nonlinear Dynamics, Psychology, and Life Sciences
JF - Nonlinear Dynamics, Psychology, and Life Sciences
IS - 2
ER -