Conserved (CT)n.(GA)n repeats in the non-coding regions at the Gpdh locus are binding sites for the GAGA factor in Drosophila melanogaster and its sibling species

E. B. Tchoubrieva; J. B. Gibson

doi:10.1023/B:GENE.0000019922.36436.3c

Conserved (CT)_n.(GA)_n repeats in the non-coding regions at the Gpdh locus are binding sites for the GAGA factor in Drosophila melanogaster and its sibling species

E. B. Tchoubrieva, J. B. Gibson^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

The (CT)_n.(GA)_n rich sequences in the upstream and 5′ intron enhancer regions of the sn-glycerol-3-phosphate dehydrogenase (Gpdh) gene in Drosophila melanogaster, its sibling and distantly related species are conserved in their position and in the number of repeats. Using in vitro DNA-footprint analyses we show that the GAGA factor binds to these multiple closely spaced and overlapping conserved (CT)_n.(GA) _n repeats in D. melanogaster and D. erecta.

Original language	English
Pages (from-to)	55-63
Number of pages	9
Journal	Genetica
Volume	121
Issue number	1
DOIs	https://doi.org/10.1023/B:GENE.0000019922.36436.3c
Publication status	Published - May 2004

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title = "Conserved (CT)n.(GA)n repeats in the non-coding regions at the Gpdh locus are binding sites for the GAGA factor in Drosophila melanogaster and its sibling species",

abstract = "The (CT)n.(GA)n rich sequences in the upstream and 5′ intron enhancer regions of the sn-glycerol-3-phosphate dehydrogenase (Gpdh) gene in Drosophila melanogaster, its sibling and distantly related species are conserved in their position and in the number of repeats. Using in vitro DNA-footprint analyses we show that the GAGA factor binds to these multiple closely spaced and overlapping conserved (CT)n.(GA) n repeats in D. melanogaster and D. erecta.",

keywords = "(CT).(GA) repeats, Evolution, GAGA, Glycerol-3-phosphate dehydrogenase, Intron, Regulation",

author = "Tchoubrieva, {E. B.} and Gibson, {J. B.}",

year = "2004",

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doi = "10.1023/B:GENE.0000019922.36436.3c",

language = "English",

volume = "121",

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T1 - Conserved (CT)n.(GA)n repeats in the non-coding regions at the Gpdh locus are binding sites for the GAGA factor in Drosophila melanogaster and its sibling species

AU - Tchoubrieva, E. B.

AU - Gibson, J. B.

PY - 2004/5

Y1 - 2004/5

N2 - The (CT)n.(GA)n rich sequences in the upstream and 5′ intron enhancer regions of the sn-glycerol-3-phosphate dehydrogenase (Gpdh) gene in Drosophila melanogaster, its sibling and distantly related species are conserved in their position and in the number of repeats. Using in vitro DNA-footprint analyses we show that the GAGA factor binds to these multiple closely spaced and overlapping conserved (CT)n.(GA) n repeats in D. melanogaster and D. erecta.

AB - The (CT)n.(GA)n rich sequences in the upstream and 5′ intron enhancer regions of the sn-glycerol-3-phosphate dehydrogenase (Gpdh) gene in Drosophila melanogaster, its sibling and distantly related species are conserved in their position and in the number of repeats. Using in vitro DNA-footprint analyses we show that the GAGA factor binds to these multiple closely spaced and overlapping conserved (CT)n.(GA) n repeats in D. melanogaster and D. erecta.

KW - (CT).(GA) repeats

KW - Evolution

KW - GAGA

KW - Glycerol-3-phosphate dehydrogenase

KW - Intron

KW - Regulation

UR - http://www.scopus.com/inward/record.url?scp=1842483212&partnerID=8YFLogxK

U2 - 10.1023/B:GENE.0000019922.36436.3c

DO - 10.1023/B:GENE.0000019922.36436.3c

M3 - Article

SN - 0016-6707

VL - 121

SP - 55

EP - 63

JO - Genetica

JF - Genetica

IS - 1

ER -

Conserved (CT)_n.(GA)_n repeats in the non-coding regions at the Gpdh locus are binding sites for the GAGA factor in Drosophila melanogaster and its sibling species

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