TY - JOUR
T1 - Controlling emerging infectious diseases like SARS
AU - Becker, Niels G.
AU - Glass, Kathryn
AU - Li, Zhengfeng
AU - Aldis, Geoffrey K.
PY - 2005/2
Y1 - 2005/2
N2 - To control emerging infectious diseases like SARS, it is necessary to resort to basic control measures that limit exposures to infectious individuals. These measures include isolating cases at diagnosis, quarantining household members and tracing contacts of diagnosed cases, providing the community with advice on how to reduce exposures, and closing schools. To justify such intervention it is important to understand how well each of these measures helps to limit transmission. In this paper, we determine the effect of a number of different interventions on the effective reproduction number and estimate requirements to achieve elimination of the infectious disease. We find that the strategy of tracing and quarantining contacts of diagnosed cases can be very successful in reducing transmission.
AB - To control emerging infectious diseases like SARS, it is necessary to resort to basic control measures that limit exposures to infectious individuals. These measures include isolating cases at diagnosis, quarantining household members and tracing contacts of diagnosed cases, providing the community with advice on how to reduce exposures, and closing schools. To justify such intervention it is important to understand how well each of these measures helps to limit transmission. In this paper, we determine the effect of a number of different interventions on the effective reproduction number and estimate requirements to achieve elimination of the infectious disease. We find that the strategy of tracing and quarantining contacts of diagnosed cases can be very successful in reducing transmission.
KW - Basic reproduction number
KW - Control of outbreaks
KW - Effective reproduction number
KW - Elimination of an infection
KW - Emerging infections
KW - Epidemic control
UR - http://www.scopus.com/inward/record.url?scp=14644431844&partnerID=8YFLogxK
U2 - 10.1016/j.mbs.2004.07.006
DO - 10.1016/j.mbs.2004.07.006
M3 - Article
SN - 0025-5564
VL - 193
SP - 205
EP - 221
JO - Mathematical Biosciences
JF - Mathematical Biosciences
IS - 2
ER -