TY - JOUR
T1 - Convergence and Equilibria Analysis of a Networked Bivirus Epidemic Model
AU - Ye, Mengbin
AU - Anderson, Brian D. O.
AU - Liu, Ji
N1 - Publisher Copyright:
© 2022 Society for Industrial and Applied Mathematics
PY - 2022
Y1 - 2022
N2 - This paper studies a networked bivirus model, in which two competing viruses spread across a network of interconnected populations; each node represents a population with a large number of individuals. The viruses may spread through possibly different network structures, and an individual cannot be simultaneously infected with both viruses. Focusing on convergence and equilibria analysis, a number of new results are provided. First, we show that for networks with generic system parameters, there exist a finite number of equilibria. Exploiting monotone systems theory, we further prove that for bivirus networks with generic system parameters, convergence to an equilibrium occurs for all initial conditions, except possibly for a set of measure zero. Given the network structure of one virus, a method is presented to construct an infinite family of network structures for the other virus that results in an infinite number of equilibria in which both viruses coexist. Necessary and sufficient conditions are derived for the local stability/instability of boundary equilibria, in which one virus is present and the other is extinct. A sufficient condition for a boundary equilibrium to be almost globally stable is presented. Then, we show how to use monotone systems theory to generate conclusions on the ordering of stable and unstable equilibria, and in some instances identify the number of equilibria via rapid simulation testing. Last, we provide an analytical method for computing equilibria in networks with only two nodes, and show that it is possible for a bivirus network to have an unstable coexistence equilibrium and two locally stable boundary equilibria.
AB - This paper studies a networked bivirus model, in which two competing viruses spread across a network of interconnected populations; each node represents a population with a large number of individuals. The viruses may spread through possibly different network structures, and an individual cannot be simultaneously infected with both viruses. Focusing on convergence and equilibria analysis, a number of new results are provided. First, we show that for networks with generic system parameters, there exist a finite number of equilibria. Exploiting monotone systems theory, we further prove that for bivirus networks with generic system parameters, convergence to an equilibrium occurs for all initial conditions, except possibly for a set of measure zero. Given the network structure of one virus, a method is presented to construct an infinite family of network structures for the other virus that results in an infinite number of equilibria in which both viruses coexist. Necessary and sufficient conditions are derived for the local stability/instability of boundary equilibria, in which one virus is present and the other is extinct. A sufficient condition for a boundary equilibrium to be almost globally stable is presented. Then, we show how to use monotone systems theory to generate conclusions on the ordering of stable and unstable equilibria, and in some instances identify the number of equilibria via rapid simulation testing. Last, we provide an analytical method for computing equilibria in networks with only two nodes, and show that it is possible for a bivirus network to have an unstable coexistence equilibrium and two locally stable boundary equilibria.
KW - competitive epidemics
KW - dynamical systems
KW - monotone systems
KW - networked systems
KW - susceptible-infected-susceptible (SIS) model
UR - http://www.scopus.com/inward/record.url?scp=85130606874&partnerID=8YFLogxK
U2 - 10.1137/20M1369014
DO - 10.1137/20M1369014
M3 - Article
SN - 0363-0129
VL - 60
SP - S323-S346
JO - SIAM Journal on Control and Optimization
JF - SIAM Journal on Control and Optimization
IS - 2
ER -