Creatine as a booster for human brain function. How might it work?

Caroline D. Rae*, Stefan Bröer

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    79 Citations (Scopus)

    Abstract

    Creatine, a naturally occurring nitrogenous organic acid found in animal tissues, has been found to play key roles in the brain including buffering energy supply, improving mitochondrial efficiency, directly acting as an anti-oxidant and acting as a neuroprotectant. Much of the evidence for these roles has been established in vitro or in pre-clinical studies. Here, we examine the roles of creatine and explore the current status of translation of this research into use in humans and the clinic. Some further possibilities for use of creatine in humans are also discussed.

    Original languageEnglish
    Pages (from-to)249-259
    Number of pages11
    JournalNeurochemistry International
    Volume89
    DOIs
    Publication statusPublished - 1 Oct 2015

    Fingerprint

    Dive into the research topics of 'Creatine as a booster for human brain function. How might it work?'. Together they form a unique fingerprint.

    Cite this