Current developments in genetically manipulated mice

Klaus I. Matthaei

doi:10.1007/978-1-60327-905-5_8

Current developments in genetically manipulated mice

Klaus I. Matthaei^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

The use of genetically manipulated mice in medical research is one of the premier tools for the study of genetic diseases. I describe here our routine methods to produce these animals that have proven to be highly reliable as well as give exceptionally high rates of germline transmission with all strains of embryonic stem cells that we have used.

Original language	English
Title of host publication	Trends in Stem Cell Biology and Technology
Publisher	Humana Press
Pages	123-136
Number of pages	14
ISBN (Print)	9781603279048
DOIs	https://doi.org/10.1007/978-1-60327-905-5_8
Publication status	Published - 2009

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title = "Current developments in genetically manipulated mice",

abstract = "The use of genetically manipulated mice in medical research is one of the premier tools for the study of genetic diseases. I describe here our routine methods to produce these animals that have proven to be highly reliable as well as give exceptionally high rates of germline transmission with all strains of embryonic stem cells that we have used.",

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KW - Germline transmission

KW - Homologous recombination

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Current developments in genetically manipulated mice

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