Cytokine responses in virus infections: Effects on pathogenesis, recovery and persistence

Marie J. Estcourt*, Ian A. Ramshaw, Alistair J. Ramsay

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    27 Citations (Scopus)

    Abstract

    During the past year, significant advances have been made in our understanding of cytokine regulation and the respective roles played by T helper cells type 1 and 2 immune responses during virus infection. Numerous mechanisms by which viruses may evade host immune defences have now been identified, some directly influencing cytokine activity. Major advances have also been made in delineating the roles of cytokines and chemokines at different stages in the pathogenesis of HIV infection.

    Original languageEnglish
    Pages (from-to)411-418
    Number of pages8
    JournalCurrent Opinion in Microbiology
    Volume1
    Issue number4
    DOIs
    Publication statusPublished - Aug 1998

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