TY - JOUR
T1 - Design and synthesis of new functionalized isoindigo and (3Z,3′Z)-3,3′-(ethane-1,2-diylidene)bis(indolin-2-one) derivatives
AU - Khalili, Gholamhossein
AU - Willis, Anthony C.
AU - Keller, Paul A.
N1 - Publisher Copyright:
© 2018, Springer-Verlag GmbH Austria, part of Springer Nature.
PY - 2018/11/1
Y1 - 2018/11/1
N2 - Abstract: A library of N,N-substituted isoindigo derivatives were prepared by reaction of isoindigo with a variety of alkylating agents in the presence of MeONa under mild conditions in yields of 65–80%. A new, more efficient synthesis of (3Z,3′Z)-3,3′-(ethane-1,2-diylidene)bis(indolin-2-one) is described by reaction of oxindole with glyoxal at reflux in methanol—a small library of N,N′-substituted derivatives were also prepared in 60–70% yield. Graphical abstract: [Figure not available: see fulltext.].
AB - Abstract: A library of N,N-substituted isoindigo derivatives were prepared by reaction of isoindigo with a variety of alkylating agents in the presence of MeONa under mild conditions in yields of 65–80%. A new, more efficient synthesis of (3Z,3′Z)-3,3′-(ethane-1,2-diylidene)bis(indolin-2-one) is described by reaction of oxindole with glyoxal at reflux in methanol—a small library of N,N′-substituted derivatives were also prepared in 60–70% yield. Graphical abstract: [Figure not available: see fulltext.].
KW - (3Z,3′Z)-3,3′-(Ethane-1,2-diylidene)bis(indolin-2-one)
KW - Isoindigo
KW - Oxindole
UR - http://www.scopus.com/inward/record.url?scp=85052912868&partnerID=8YFLogxK
U2 - 10.1007/s00706-018-2272-1
DO - 10.1007/s00706-018-2272-1
M3 - Article
SN - 0026-9247
VL - 149
SP - 2103
EP - 2111
JO - Monatshefte fur Chemie
JF - Monatshefte fur Chemie
IS - 11
ER -