Detecting Genetic Recombination

Georg Weiller

    Research output: Chapter in Book/Report/Conference proceedingChapterpeer-review

    Abstract

    Recombination is the major motor of evolution. While mutations result in gradual changes, recombination reshuffles entire functional modules and thus progresses evolution in leaps and bounds. We need to identify recombination breakpoints in sequences to understand the evolutionary process, the impact of recombination, and to reconstruct the phylogenetic history of genes and genomes. This chapter provides a step by step guide for detecting recombination even in large and complex sequence alignments.
    Original languageEnglish
    Title of host publicationMethods in Molecular Biology: Bioinformatics: Data, Sequence Analysis and Evolution
    EditorsJonathan Keith
    Place of PublicationUSA
    PublisherHumana Press Inc.
    Pages471-483
    Volume1
    Edition1st
    ISBN (Print)9781588297075
    DOIs
    Publication statusPublished - 2008

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