Determination of molecular hydration in solution via changes in magnetic anisotropy

Marcus J. Giansiracusa; Michele Vonci; Yasmin L. Whyatt; Carys Williams; Kevin Mason; David Parker; Eric J. L. McInnes; Nicholas F. Chilton

doi:10.1039/D3CC00601H

Determination of molecular hydration in solution via changes in magnetic anisotropy

Marcus J. Giansiracusa, Michele Vonci, Yasmin L. Whyatt, Carys Williams, Kevin Mason, David Parker^*, Eric J. L. McInnes^*, Nicholas F. Chilton^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

Abstract

The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. Determination of hydration is difficult, and various optical and NMR-based techniques have been used. Here we use EPR spectroscopy to unambiguously demonstrate that a t -butyl-pyridyl-functionalised Er III DOTA derivative coordinates water, while its methylphosphinate analogue does not.

Original language	English
Pages (from-to)	4531-4534
Number of pages	4
Journal	Chemical Communications
Volume	59
Issue number	30
Early online date	20 Mar 2023
DOIs	https://doi.org/10.1039/D3CC00601H
Publication status	Published - 18 Apr 2023
Externally published	Yes

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title = "Determination of molecular hydration in solution via changes in magnetic anisotropy",

abstract = "The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. Determination of hydration is difficult, and various optical and NMR-based techniques have been used. Here we use EPR spectroscopy to unambiguously demonstrate that a t -butyl-pyridyl-functionalised Er III DOTA derivative coordinates water, while its methylphosphinate analogue does not.",

author = "Giansiracusa, {Marcus J.} and Michele Vonci and Whyatt, {Yasmin L.} and Carys Williams and Kevin Mason and David Parker and McInnes, {Eric J. L.} and Chilton, {Nicholas F.}",

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doi = "10.1039/D3CC00601H",

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T1 - Determination of molecular hydration in solution via changes in magnetic anisotropy

AU - Giansiracusa, Marcus J.

AU - Vonci, Michele

AU - Whyatt, Yasmin L.

AU - Williams, Carys

AU - Mason, Kevin

AU - Parker, David

AU - McInnes, Eric J. L.

AU - Chilton, Nicholas F.

PY - 2023/4/18

Y1 - 2023/4/18

N2 - The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. Determination of hydration is difficult, and various optical and NMR-based techniques have been used. Here we use EPR spectroscopy to unambiguously demonstrate that a t -butyl-pyridyl-functionalised Er III DOTA derivative coordinates water, while its methylphosphinate analogue does not.

AB - The hydration behaviour of coordination complexes is important for understanding their roles as bio-imaging agents. Determination of hydration is difficult, and various optical and NMR-based techniques have been used. Here we use EPR spectroscopy to unambiguously demonstrate that a t -butyl-pyridyl-functionalised Er III DOTA derivative coordinates water, while its methylphosphinate analogue does not.

U2 - 10.1039/D3CC00601H

DO - 10.1039/D3CC00601H

M3 - Article

SN - 1359-7345

VL - 59

SP - 4531

EP - 4534

JO - Chemical Communications

JF - Chemical Communications

IS - 30

ER -

Determination of molecular hydration in solution via changes in magnetic anisotropy

Abstract

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