Devil Facial Tumour Disease (DFTD): Using genetics and genomics to investigate infectious disease in an endangered marsupial

Hannah S. Bender

doi:10.1007/978-90-481-9023-2_23

Devil Facial Tumour Disease (DFTD): Using genetics and genomics to investigate infectious disease in an endangered marsupial

Hannah S. Bender^*

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

The Tasmanian devil (Sarcophilus harrisii), so named for its blood-curdling, nocturnal shrieks and snarls, is the largest of the carnivorous marsupials. Although once widely persecuted, concerted efforts are now being made to save the devil from extinction following the emergence of a fatal transmissible malignancy known as devil facial tumour disease (DFTD). DFTD is unusual in that the infectious agent is the cancer cell itself. This chapter discusses the aetiology and pathogenesis of DFTD as well as the profound impact the spread of DFTD has had on the devil's conservation status. Strategies for managing DFTD and conserving the devil will be explored and the contribution of new sequencing technology to the field of conservation genetics and genomics will be examined with regard to the Tasmanian devil and DFTD.

Original language	English
Title of host publication	Marsupial Genetics and Genomics
Publisher	Springer Netherlands
Pages	499-515
Number of pages	17
ISBN (Electronic)	9789048190232
ISBN (Print)	9789048190225
DOIs	https://doi.org/10.1007/978-90-481-9023-2_23
Publication status	Published - 2010

Access to Document

10.1007/978-90-481-9023-2_23

Cite this

@inbook{e2ba631cf80949059f07fed087250707,

title = "Devil Facial Tumour Disease (DFTD): Using genetics and genomics to investigate infectious disease in an endangered marsupial",

abstract = "The Tasmanian devil (Sarcophilus harrisii), so named for its blood-curdling, nocturnal shrieks and snarls, is the largest of the carnivorous marsupials. Although once widely persecuted, concerted efforts are now being made to save the devil from extinction following the emergence of a fatal transmissible malignancy known as devil facial tumour disease (DFTD). DFTD is unusual in that the infectious agent is the cancer cell itself. This chapter discusses the aetiology and pathogenesis of DFTD as well as the profound impact the spread of DFTD has had on the devil's conservation status. Strategies for managing DFTD and conserving the devil will be explored and the contribution of new sequencing technology to the field of conservation genetics and genomics will be examined with regard to the Tasmanian devil and DFTD.",

keywords = "Conservation genetics, Devil facial tumour disease, Genomics, Tasmanian devil, Wildlife disease",

author = "Bender, \{Hannah S.\}",

note = "Publisher Copyright: {\textcopyright} Springer Science+Business Media B.V. 2010.",

year = "2010",

doi = "10.1007/978-90-481-9023-2\_23",

language = "English",

isbn = "9789048190225",

pages = "499--515",

booktitle = "Marsupial Genetics and Genomics",

publisher = "Springer Netherlands",

address = "Netherlands",

}

TY - CHAP

T1 - Devil Facial Tumour Disease (DFTD)

T2 - Using genetics and genomics to investigate infectious disease in an endangered marsupial

AU - Bender, Hannah S.

N1 - Publisher Copyright: © Springer Science+Business Media B.V. 2010.

PY - 2010

Y1 - 2010

N2 - The Tasmanian devil (Sarcophilus harrisii), so named for its blood-curdling, nocturnal shrieks and snarls, is the largest of the carnivorous marsupials. Although once widely persecuted, concerted efforts are now being made to save the devil from extinction following the emergence of a fatal transmissible malignancy known as devil facial tumour disease (DFTD). DFTD is unusual in that the infectious agent is the cancer cell itself. This chapter discusses the aetiology and pathogenesis of DFTD as well as the profound impact the spread of DFTD has had on the devil's conservation status. Strategies for managing DFTD and conserving the devil will be explored and the contribution of new sequencing technology to the field of conservation genetics and genomics will be examined with regard to the Tasmanian devil and DFTD.

AB - The Tasmanian devil (Sarcophilus harrisii), so named for its blood-curdling, nocturnal shrieks and snarls, is the largest of the carnivorous marsupials. Although once widely persecuted, concerted efforts are now being made to save the devil from extinction following the emergence of a fatal transmissible malignancy known as devil facial tumour disease (DFTD). DFTD is unusual in that the infectious agent is the cancer cell itself. This chapter discusses the aetiology and pathogenesis of DFTD as well as the profound impact the spread of DFTD has had on the devil's conservation status. Strategies for managing DFTD and conserving the devil will be explored and the contribution of new sequencing technology to the field of conservation genetics and genomics will be examined with regard to the Tasmanian devil and DFTD.

KW - Conservation genetics

KW - Devil facial tumour disease

KW - Genomics

KW - Tasmanian devil

KW - Wildlife disease

UR - https://www.scopus.com/pages/publications/84919734058

U2 - 10.1007/978-90-481-9023-2_23

DO - 10.1007/978-90-481-9023-2_23

M3 - Chapter

SN - 9789048190225

SP - 499

EP - 515

BT - Marsupial Genetics and Genomics

PB - Springer Netherlands

ER -

Devil Facial Tumour Disease (DFTD): Using genetics and genomics to investigate infectious disease in an endangered marsupial

Abstract

Access to Document

Other files and links

Fingerprint

Cite this