Direct regulation of shikimate, early phenylpropanoid, and stilbenoid pathways by Subgroup 2 R2R3-MYBs in grapevine

Luis Orduña, Miaomiao Li, David Navarro-Payá, Chen Zhang, Antonio Santiago, Pablo Romero, Živa Ramšak, Gabriele Magon, Janine Höll, Patrick Merz, Kristina Gruden, Alessandro Vannozzi, Dario Cantu, Jochen Bogs, Darren C.J. Wong, Shao shan Carol Huang, José Tomás Matus*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    25 Citations (Scopus)

    Abstract

    Subgroup 2 R2R3 MYBs have been shown to upregulate stilbene synthase expression in grapevine; however, their broader roles in the regulation of secondary metabolism remained unclear. Combining whole genome gene co-expression networks, cistrome data for MYB13/14/15, and MYB15 overexpression we identified new regulatory targets across stilbenoid, early phenylpropanoid and shikimate pathways. We demonstrate the validity of this approach via the biochemical characterization of new ROMT targets and provide the networks and cistrome data to the community.
    Original languageEnglish
    Pages (from-to)529-547
    Number of pages19
    JournalPlant Journal
    Volume110
    Issue number2
    DOIs
    Publication statusPublished - Apr 2022

    Fingerprint

    Dive into the research topics of 'Direct regulation of shikimate, early phenylpropanoid, and stilbenoid pathways by Subgroup 2 R2R3-MYBs in grapevine'. Together they form a unique fingerprint.

    Cite this