Discriminating microbe from self suffers a double toll

Christopher C. Goodnow

doi:10.1126/science.1129797

Discriminating microbe from self suffers a double toll

Christopher C. Goodnow^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

19 Citations (Scopus)

Abstract

The autoimmune disease lupus is caused by immune cells that secrete antibodies to the patient's own antigens. A mouse version of the disease reveals two genes that lead to this disregulation.

Original language	English
Pages (from-to)	1606-1608
Number of pages	3
Journal	Science
Volume	312
Issue number	5780
DOIs	https://doi.org/10.1126/science.1129797
Publication status	Published - 16 Jun 2006

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title = "Discriminating microbe from self suffers a double toll",

abstract = "The autoimmune disease lupus is caused by immune cells that secrete antibodies to the patient's own antigens. A mouse version of the disease reveals two genes that lead to this disregulation.",

author = "Goodnow, \{Christopher C.\}",

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AB - The autoimmune disease lupus is caused by immune cells that secrete antibodies to the patient's own antigens. A mouse version of the disease reveals two genes that lead to this disregulation.

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DO - 10.1126/science.1129797

M3 - Review article

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EP - 1608

JO - Science

JF - Science

IS - 5780

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Discriminating microbe from self suffers a double toll

Abstract

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