@inbook{a7cd2ba294ab4f44b94582a2567775ed,
title = "Ecology and Evolution of Betacoronaviruses",
abstract = "The crown-like outline of the virions of coronaviruses will long endure as the iconic image of 2020 – the year of the COVID-19 pandemic. This major human health emergency has been caused by a betacoronavirus, as have others in the past. In this chapter, we outline the taxonomy of betacoronaviruses and their properties, both genetic and biological. We discuss their recombinational and mutational histories separately to show that the sequence of the RaTG13 bat virus isolate is the closest currently known full-length genetic homolog of that of the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2). However, the RaTG13 bat virus and SARS-CoV-2 have probably diverged over 20 years. We discuss the ecology of their pangolin and bat hosts and conclude that, like other recent viral pandemics, the underlying cause of the SARS-CoV-2 emergence is probably the relentless growth of the world{\textquoteright}s human population and the overexploitation and disturbance of the environment.",
keywords = "Betacoronaviruses, Coronaviruses, Ecology, Emergence, Evolution, Phylogeny, SARS-CoV-2",
author = "Eduardo Rodr{\'i}guez-Rom{\'a}n and Gibbs, {Adrian J.}",
note = "Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.",
year = "2021",
doi = "10.1007/978-3-030-63761-3_3",
language = "English",
series = "Advances in Experimental Medicine and Biology",
publisher = "Springer",
pages = "41--60",
booktitle = "Advances in Experimental Medicine and Biology",
address = "Germany",
}