Effect of the surface topographic modification on cytocompatibility of hardened calcium phosphate cement

Jiyan Li; Fupo He; Jiandong Ye

doi:10.1016/j.apsusc.2013.03.023

Effect of the surface topographic modification on cytocompatibility of hardened calcium phosphate cement

Jiyan Li, Fupo He, Jiandong Ye^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

As cells are inherently sensitive to local nanoscale patterns of topography, the aim of this study was to determine the effect of the topographic modification of hardened calcium phosphate cement on cell response which was conducted with MC3T3-E1 cells. The results exhibited that the samples with regular blade-like crystalline structure had better cell response (cell attachment, viability, proliferation and differentiation) compared to those with irregular blade-like crystalline structure. The method of topographic modification is promising for developing a novel biomaterial of hardened calcium phosphate cement for bone repair.

Original language	English
Pages (from-to)	237-240
Number of pages	4
Journal	Applied Surface Science
Volume	274
DOIs	https://doi.org/10.1016/j.apsusc.2013.03.023
Publication status	Published - 1 Jun 2013
Externally published	Yes

Cite this

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title = "Effect of the surface topographic modification on cytocompatibility of hardened calcium phosphate cement",

abstract = "As cells are inherently sensitive to local nanoscale patterns of topography, the aim of this study was to determine the effect of the topographic modification of hardened calcium phosphate cement on cell response which was conducted with MC3T3-E1 cells. The results exhibited that the samples with regular blade-like crystalline structure had better cell response (cell attachment, viability, proliferation and differentiation) compared to those with irregular blade-like crystalline structure. The method of topographic modification is promising for developing a novel biomaterial of hardened calcium phosphate cement for bone repair.",

keywords = "Calcium phosphate cement, Cell response, Topography",

author = "Jiyan Li and Fupo He and Jiandong Ye",

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T1 - Effect of the surface topographic modification on cytocompatibility of hardened calcium phosphate cement

AU - Li, Jiyan

AU - He, Fupo

AU - Ye, Jiandong

PY - 2013/6/1

Y1 - 2013/6/1

N2 - As cells are inherently sensitive to local nanoscale patterns of topography, the aim of this study was to determine the effect of the topographic modification of hardened calcium phosphate cement on cell response which was conducted with MC3T3-E1 cells. The results exhibited that the samples with regular blade-like crystalline structure had better cell response (cell attachment, viability, proliferation and differentiation) compared to those with irregular blade-like crystalline structure. The method of topographic modification is promising for developing a novel biomaterial of hardened calcium phosphate cement for bone repair.

AB - As cells are inherently sensitive to local nanoscale patterns of topography, the aim of this study was to determine the effect of the topographic modification of hardened calcium phosphate cement on cell response which was conducted with MC3T3-E1 cells. The results exhibited that the samples with regular blade-like crystalline structure had better cell response (cell attachment, viability, proliferation and differentiation) compared to those with irregular blade-like crystalline structure. The method of topographic modification is promising for developing a novel biomaterial of hardened calcium phosphate cement for bone repair.

KW - Calcium phosphate cement

KW - Cell response

KW - Topography

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U2 - 10.1016/j.apsusc.2013.03.023

DO - 10.1016/j.apsusc.2013.03.023

M3 - Article

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VL - 274

SP - 237

EP - 240

JO - Applied Surface Science

JF - Applied Surface Science

ER -

Effect of the surface topographic modification on cytocompatibility of hardened calcium phosphate cement

Abstract

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