TY - GEN
T1 - Ellipsometric study of ferritin clusters adsorbed on metasurface and influenced by UV irradiation
AU - Tanovska, M.
AU - Rahmani, M.
AU - Zografov, N.
AU - Vladimirova-Mihaleva, L.
AU - Neshev, D.
N1 - Publisher Copyright:
© 2019 IEEE.
PY - 2019/9
Y1 - 2019/9
N2 - In the last decade, the metasurfaces tend to be used as a successful biosensing materials. In this study, amorphous silicon arrays of resonant nanostructures were used as a substrate for Ferritin protein adsorption. Ferritins are iron-storing proteins that play an essential role in the biochemical reactions and the iron transport of all living organisms. This study is motivated by the increased number of neurodegenerative and cancer diseases, where Ferritin plays a key role. The properties of the Ferritin clusters, adsorbed on a dielectric metasurface, were studied ellipsometrically as a function of UV irradiation. Our results show that the properties of the Ferritin clusters depend on the UV exposure time. Resulting either in an increase of the molecular density due to release of iron ions or in the deformation of the quaternary protein structure. The data show that the metasurfaces are applicable for analysis and characterization of biomolecules by ellipsometry.
AB - In the last decade, the metasurfaces tend to be used as a successful biosensing materials. In this study, amorphous silicon arrays of resonant nanostructures were used as a substrate for Ferritin protein adsorption. Ferritins are iron-storing proteins that play an essential role in the biochemical reactions and the iron transport of all living organisms. This study is motivated by the increased number of neurodegenerative and cancer diseases, where Ferritin plays a key role. The properties of the Ferritin clusters, adsorbed on a dielectric metasurface, were studied ellipsometrically as a function of UV irradiation. Our results show that the properties of the Ferritin clusters depend on the UV exposure time. Resulting either in an increase of the molecular density due to release of iron ions or in the deformation of the quaternary protein structure. The data show that the metasurfaces are applicable for analysis and characterization of biomolecules by ellipsometry.
UR - http://www.scopus.com/inward/record.url?scp=85075615468&partnerID=8YFLogxK
U2 - 10.1109/MetaMaterials.2019.8900873
DO - 10.1109/MetaMaterials.2019.8900873
M3 - Conference contribution
T3 - 2019 13th International Congress on Artificial Materials for Novel Wave Phenomena, Metamaterials 2019
SP - X501-X504
BT - 2019 13th International Congress on Artificial Materials for Novel Wave Phenomena, Metamaterials 2019
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 13th International Congress on Artificial Materials for Novel Wave Phenomena, Metamaterials 2019
Y2 - 16 September 2019 through 21 September 2019
ER -