Abstract
The equilibrium constant for the gliotoxin/glutathione pair was found to be 1200±100M-1 at pH 7.0 at 25°C. Under conditions where the reaction was quenched rapidly with the addition of acid, gliotoxin-glutathione conjugate adducts were detected.
Original language | English |
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Pages (from-to) | 483-485 |
Number of pages | 3 |
Journal | Bioorganic and Medicinal Chemistry Letters |
Volume | 11 |
Issue number | 4 |
DOIs | |
Publication status | Published - 26 Feb 2001 |