TY - JOUR
T1 - Exploring the potential of dental calculus to shed light on past human migrations in Oceania
AU - Velsko, Irina M.
AU - Fagernäs, Zandra
AU - Tromp, Monica
AU - Bedford, Stuart
AU - Buckley, Hallie R.
AU - Clark, Geoffrey
AU - Dudgeon, John
AU - Flexner, James
AU - Galipaud, Jean Christophe
AU - Kinaston, Rebecca
AU - Lewis, Cecil M.
AU - Matisoo-Smith, Elizabeth
AU - Nägele, Kathrin
AU - Ozga, Andrew T.
AU - Posth, Cosimo
AU - Rohrlach, Adam B.
AU - Shing, Richard
AU - Simanjuntak, Truman
AU - Spriggs, Matthew
AU - Tamarii, Anatauarii
AU - Valentin, Frédérique
AU - Willie, Edson
AU - Warinner, Christina
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/12
Y1 - 2024/12
N2 - The Pacific islands and Island Southeast Asia have experienced multiple waves of human migrations, providing a case study for exploring the potential of ancient microbiomes to study human migration. We perform a metagenomic study of archaeological dental calculus from 102 individuals, originating from 10 Pacific islands and 1 island in Island Southeast Asia spanning ~3000 years. Oral microbiome DNA preservation in calculus is far higher than that of human DNA in archaeological bone, and comparable to that of calculus from temperate regions. Oral microbial community composition is minimally driven by time period and geography in Pacific and Island Southeast Asia calculus, but is found to be distinctive compared to calculus from Europe, Africa, and Asia. Phylogenies of individual bacterial species in Pacific and Island Southeast Asia calculus reflect geography. Archaeological dental calculus shows good preservation in tropical regions and the potential to yield information about past human migrations, complementing studies of the human genome.
AB - The Pacific islands and Island Southeast Asia have experienced multiple waves of human migrations, providing a case study for exploring the potential of ancient microbiomes to study human migration. We perform a metagenomic study of archaeological dental calculus from 102 individuals, originating from 10 Pacific islands and 1 island in Island Southeast Asia spanning ~3000 years. Oral microbiome DNA preservation in calculus is far higher than that of human DNA in archaeological bone, and comparable to that of calculus from temperate regions. Oral microbial community composition is minimally driven by time period and geography in Pacific and Island Southeast Asia calculus, but is found to be distinctive compared to calculus from Europe, Africa, and Asia. Phylogenies of individual bacterial species in Pacific and Island Southeast Asia calculus reflect geography. Archaeological dental calculus shows good preservation in tropical regions and the potential to yield information about past human migrations, complementing studies of the human genome.
UR - http://www.scopus.com/inward/record.url?scp=85210091986&partnerID=8YFLogxK
U2 - 10.1038/s41467-024-53920-z
DO - 10.1038/s41467-024-53920-z
M3 - Article
C2 - 39582065
AN - SCOPUS:85210091986
SN - 2041-1723
VL - 15
JO - Nature Communications
JF - Nature Communications
IS - 1
M1 - 10191
ER -