Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development

Sean Grimmond; Rachel Larder; Nick Van Hateren; Pam Siggers; Sue Morse; Terry Hacker; Ruth Arkell; Andy Greenfield

doi:10.1016/S0925-4773(00)00586-4

Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development

Sean Grimmond, Rachel Larder, Nick Van Hateren, Pam Siggers, Sue Morse, Terry Hacker, Ruth Arkell, Andy Greenfield^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

46 Citations (Scopus)

Abstract

We have recently reported the preliminary characterisation of a novel EGF-related gene, Scube1 (signal peptide-CUB domain-EGF-related, gene 1), that is expressed prominently in the developing gonad, nervous system, somites, surface ectoderm and limb buds of the mouse. Here we describe the expression pattern of a closely related gene, Scube2 (also known as Cegp1), which maps to the distal region of mouse chromosome 7. Scube2 transcription is restricted to the embryonic neurectoderm but is also detectable in the adult heart, lung and testis.

Original language	English
Pages (from-to)	209-211
Number of pages	3
Journal	Mechanisms of Development
Volume	102
Issue number	1-2
DOIs	https://doi.org/10.1016/S0925-4773(00)00586-4
Publication status	Published - 2001
Externally published	Yes

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title = "Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development",

abstract = "We have recently reported the preliminary characterisation of a novel EGF-related gene, Scube1 (signal peptide-CUB domain-EGF-related, gene 1), that is expressed prominently in the developing gonad, nervous system, somites, surface ectoderm and limb buds of the mouse. Here we describe the expression pattern of a closely related gene, Scube2 (also known as Cegp1), which maps to the distal region of mouse chromosome 7. Scube2 transcription is restricted to the embryonic neurectoderm but is also detectable in the adult heart, lung and testis.",

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AU - Grimmond, Sean

AU - Larder, Rachel

AU - Van Hateren, Nick

AU - Siggers, Pam

AU - Morse, Sue

AU - Hacker, Terry

AU - Arkell, Ruth

AU - Greenfield, Andy

PY - 2001

Y1 - 2001

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AB - We have recently reported the preliminary characterisation of a novel EGF-related gene, Scube1 (signal peptide-CUB domain-EGF-related, gene 1), that is expressed prominently in the developing gonad, nervous system, somites, surface ectoderm and limb buds of the mouse. Here we describe the expression pattern of a closely related gene, Scube2 (also known as Cegp1), which maps to the distal region of mouse chromosome 7. Scube2 transcription is restricted to the embryonic neurectoderm but is also detectable in the adult heart, lung and testis.

KW - CUB domain

KW - Cegp1

KW - Epidermal growth factor-related

KW - Mouse chromosome 7

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KW - Neurepithelium

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VL - 102

SP - 209

EP - 211

JO - Mechanisms of Development

JF - Mechanisms of Development

IS - 1-2

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Expression of a novel mammalian epidermal growth factor-related gene during mouse neural development

Abstract

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