Finding a Needle in a Haystack – In Silico Search for Environmental Traces of Candida auris

Laszlo Irinyi, Michael Roper, Richard Malik, Wieland Meyer

    Research output: Contribution to journalArticlepeer-review

    10 Citations (Scopus)

    Abstract

    Candida auris, first described from an ear infection in Japan, is the most talked about multidrug resistant emerging pathogenic fungal species. Its environmental niche remained a mystery until its first isolation from wetlands of the Andaman Islands, India in 2020. We screened a subset of the world's largest sequence repository, the Sequence Read Archive at NCBI using a DNA metabarcoding approach, based on either the ITS1 or ITS2 region of the official primary fungal DNA barcode, to identify potential environmental sources of C. auris. Our search identified 34 matches with partial C. auris ITS sequences from seven metabarcoding studies, providing wider evidence for the presence of C. auris outside human-maintained facilities.
    Original languageEnglish
    Pages (from-to)490-495
    JournalJapanese Journal of Infectious Diseases
    Volume75
    Issue number5
    DOIs
    Publication statusPublished - 2022

    Fingerprint

    Dive into the research topics of 'Finding a Needle in a Haystack – In Silico Search for Environmental Traces of Candida auris'. Together they form a unique fingerprint.

    Cite this