Flow-Based Synthesis of Gold-Coated Magnetic Nanoparticles for Magnetoplasmonic Sensing Applications

Milad Mehdipour, Lucy Gloag, Daniel Hagness, Jiaxin Lian, Md Saiful Alam, Xueqian Chen, Richard D. Tilley, John Justin Gooding

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)

Abstract

Gold-coated magnetic nanoparticles are key materials for the fast separation and ultrasensitive detection of analytes in magnetoplasmonic sensors. However, the synthesis of gold-coated magnetic nanoparticles typically requires small-scale, colloidal methods over hours or days and often results in incomplete shells with variable optical properties. A robust, rapid, and scalable synthesis method is still needed to reliably form a complete gold nanoshell around magnetic nanoparticles. Herein, a new methodology for the synthesis of gold-coated magnetic nanoparticles via a flow-based manufacturing system that can easily be scaled up is presented. The developed method first produces gold-seeded silica coated magnetic nanoparticles and then a complete, tunable gold shell with relatively uniform size and shape. The flow-based method can be performed in a total time of less than 2 min, enabling rapid and complete gold coating. The particles show both excellent magnetic and plasmonic properties, which facilitates application as biosensing agents in dark-field microscopy and surface-enhanced Raman scattering.

Original languageEnglish
Article number2200051
Number of pages6
JournalParticle and Particle Systems Characterization
Volume39
Issue number8
Early online dateJun 2022
DOIs
Publication statusPublished - Aug 2022
Externally publishedYes

Fingerprint

Dive into the research topics of 'Flow-Based Synthesis of Gold-Coated Magnetic Nanoparticles for Magnetoplasmonic Sensing Applications'. Together they form a unique fingerprint.

Cite this