Fluid Homeostasis and Diuretic Therapy in the Neonate

Cara Slagle; Katja M. Gist; Michelle C. Starr; Trina S. Hemmelgarn; Stuart L. Goldstein; Alison L. Kent

doi:10.1542/neo.23-3-e189

Fluid Homeostasis and Diuretic Therapy in the Neonate

Cara Slagle, Katja M. Gist, Michelle C. Starr, Trina S. Hemmelgarn, Stuart L. Goldstein, Alison L. Kent

Research output: Contribution to journal › Review article › peer-review

2 Citations (Scopus)

Abstract

Understanding physiologic water balance and homeostasis mechanisms in the neonate is critical for clinicians in the NICU as pathologic fluid accumulation increases the risk for morbidity and mortality. In addition, once this process occurs, treatment is limited. In this review, we will cover fluid homeostasis in the neonate, explain the implications of prematurity on this process, discuss the complexity of fluid accumulation and the development of fluid overload, identify mitigation strategies, and review treatment options.

Original language	English
Pages (from-to)	e189-e204
Journal	NeoReviews
Volume	23
Issue number	3
DOIs	https://doi.org/10.1542/neo.23-3-e189
Publication status	Published - 1 Mar 2022
Externally published	Yes

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10.1542/neo.23-3-e189

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title = "Fluid Homeostasis and Diuretic Therapy in the Neonate",

abstract = "Understanding physiologic water balance and homeostasis mechanisms in the neonate is critical for clinicians in the NICU as pathologic fluid accumulation increases the risk for morbidity and mortality. In addition, once this process occurs, treatment is limited. In this review, we will cover fluid homeostasis in the neonate, explain the implications of prematurity on this process, discuss the complexity of fluid accumulation and the development of fluid overload, identify mitigation strategies, and review treatment options.",

author = "Cara Slagle and Gist, {Katja M.} and Starr, {Michelle C.} and Hemmelgarn, {Trina S.} and Goldstein, {Stuart L.} and Kent, {Alison L.}",

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AU - Gist, Katja M.

AU - Starr, Michelle C.

AU - Hemmelgarn, Trina S.

AU - Goldstein, Stuart L.

AU - Kent, Alison L.

PY - 2022/3/1

Y1 - 2022/3/1

N2 - Understanding physiologic water balance and homeostasis mechanisms in the neonate is critical for clinicians in the NICU as pathologic fluid accumulation increases the risk for morbidity and mortality. In addition, once this process occurs, treatment is limited. In this review, we will cover fluid homeostasis in the neonate, explain the implications of prematurity on this process, discuss the complexity of fluid accumulation and the development of fluid overload, identify mitigation strategies, and review treatment options.

AB - Understanding physiologic water balance and homeostasis mechanisms in the neonate is critical for clinicians in the NICU as pathologic fluid accumulation increases the risk for morbidity and mortality. In addition, once this process occurs, treatment is limited. In this review, we will cover fluid homeostasis in the neonate, explain the implications of prematurity on this process, discuss the complexity of fluid accumulation and the development of fluid overload, identify mitigation strategies, and review treatment options.

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DO - 10.1542/neo.23-3-e189

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JO - NeoReviews

JF - NeoReviews

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Fluid Homeostasis and Diuretic Therapy in the Neonate

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