Follicular regulatory T cells produce neuritin to regulate B cells

Paula Gonzalez-Figueroa; Jonathan A. Roco; Ilenia Papa; Lorena Núñez Villacís; Maurice Stanley; Michelle A. Linterman; Alexander Dent; Pablo F. Canete; Carola G. Vinuesa

doi:10.1016/j.cell.2021.02.027

Follicular regulatory T cells produce neuritin to regulate B cells

Paula Gonzalez-Figueroa
, Jonathan A. Roco
, Ilenia Papa
, Lorena Núñez Villacís
, Maurice Stanley
, Michelle A. Linterman
, Alexander Dent
, Pablo F. Canete
, Carola G. Vinuesa^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

151 Citations (SciVal)

Abstract

Follicular regulatory T cells produce an abundance of neuritin protein, which acts directly on B cells to suppress B cell-driven autoimmunity and IgE-mediated allergies.

Original language	English
Pages (from-to)	1775-1789.e19
Journal	Cell
Volume	184
Issue number	7
DOIs	https://doi.org/10.1016/j.cell.2021.02.027
Publication status	Published - 1 Apr 2021

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@article{ae64aa753d7e42569a52b49323cd71dc,

title = "Follicular regulatory T cells produce neuritin to regulate B cells",

abstract = "Follicular regulatory T cells produce an abundance of neuritin protein, which acts directly on B cells to suppress B cell-driven autoimmunity and IgE-mediated allergies.",

keywords = "IgE, autoantibodies, autoimmunity, follicular helper T (Tfh), follicular regulatory T (Tfr), germinal center (GC), neuritin",

author = "Paula Gonzalez-Figueroa and Roco, \{Jonathan A.\} and Ilenia Papa and \{N{\'u}{\~n}ez Villac{\'i}s\}, Lorena and Maurice Stanley and Linterman, \{Michelle A.\} and Alexander Dent and Canete, \{Pablo F.\} and Vinuesa, \{Carola G.\}",

note = "Publisher Copyright: {\textcopyright} 2021 Elsevier Inc.",

year = "2021",

month = apr,

day = "1",

doi = "10.1016/j.cell.2021.02.027",

language = "English",

volume = "184",

pages = "1775--1789.e19",

journal = "Cell",

issn = "0092-8674",

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number = "7",

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TY - JOUR

T1 - Follicular regulatory T cells produce neuritin to regulate B cells

AU - Gonzalez-Figueroa, Paula

AU - Roco, Jonathan A.

AU - Papa, Ilenia

AU - Núñez Villacís, Lorena

AU - Stanley, Maurice

AU - Linterman, Michelle A.

AU - Dent, Alexander

AU - Canete, Pablo F.

AU - Vinuesa, Carola G.

PY - 2021/4/1

Y1 - 2021/4/1

N2 - Follicular regulatory T cells produce an abundance of neuritin protein, which acts directly on B cells to suppress B cell-driven autoimmunity and IgE-mediated allergies.

AB - Follicular regulatory T cells produce an abundance of neuritin protein, which acts directly on B cells to suppress B cell-driven autoimmunity and IgE-mediated allergies.

KW - IgE

KW - autoantibodies

KW - autoimmunity

KW - follicular helper T (Tfh)

KW - follicular regulatory T (Tfr)

KW - germinal center (GC)

KW - neuritin

UR - https://www.scopus.com/pages/publications/85102442393

U2 - 10.1016/j.cell.2021.02.027

DO - 10.1016/j.cell.2021.02.027

M3 - Article

SN - 0092-8674

VL - 184

SP - 1775-1789.e19

JO - Cell

JF - Cell

IS - 7

ER -

Follicular regulatory T cells produce neuritin to regulate B cells

Abstract

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