Formal total synthesis of triptolide

Natalie A. Miller; Anthony C. Willis; Michael S. Sherburn

doi:10.1039/b718754h

Formal total synthesis of triptolide

Natalie A. Miller, Anthony C. Willis^*, Michael S. Sherburn

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

46 Citations (SciVal)

Abstract

A new approach to the medicinally-important natural product triptolide is significantly shorter than previous syntheses, highly convergent and avoids the use of protecting groups; key features include two Diels-Alder reactions and a new deoxygenative aromatisation process.

Original language	English
Pages (from-to)	1226-1228
Number of pages	3
Journal	Chemical Communications
Issue number	10
DOIs	https://doi.org/10.1039/b718754h
Publication status	Published - 2008

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title = "Formal total synthesis of triptolide",

abstract = "A new approach to the medicinally-important natural product triptolide is significantly shorter than previous syntheses, highly convergent and avoids the use of protecting groups; key features include two Diels-Alder reactions and a new deoxygenative aromatisation process.",

author = "Miller, {Natalie A.} and Willis, {Anthony C.} and Sherburn, {Michael S.}",

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Formal total synthesis of triptolide

Abstract

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