FUBP/KH domain proteins in transcription: Back to the future

Leonie M. Quinn

doi:10.1080/21541264.2017.1293595

FUBP/KH domain proteins in transcription: Back to the future

Leonie M. Quinn^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

11 Citations (Scopus)

Abstract

Drosophila genetic studies demonstrate that cell and tissue growth regulation is a primary developmental function of P-element somatic inhibitor (Psi), the sole ortholog of FUBP family RNA/DNA-binding proteins. Psi achieves growth control through interaction with Mediator, observations that should put to rest controversy surrounding Pol II transcriptional functions for these KH domain proteins.

Original language	English
Pages (from-to)	185-192
Number of pages	8
Journal	Transcription
Volume	8
Issue number	3
DOIs	https://doi.org/10.1080/21541264.2017.1293595
Publication status	Published - 27 May 2017

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10.1080/21541264.2017.1293595

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title = "FUBP/KH domain proteins in transcription: Back to the future",

abstract = "Drosophila genetic studies demonstrate that cell and tissue growth regulation is a primary developmental function of P-element somatic inhibitor (Psi), the sole ortholog of FUBP family RNA/DNA-binding proteins. Psi achieves growth control through interaction with Mediator, observations that should put to rest controversy surrounding Pol II transcriptional functions for these KH domain proteins.",

keywords = "Drosophila, FUBP1, Growth control, MYC, Psi",

author = "Quinn, {Leonie M.}",

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T2 - Back to the future

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N2 - Drosophila genetic studies demonstrate that cell and tissue growth regulation is a primary developmental function of P-element somatic inhibitor (Psi), the sole ortholog of FUBP family RNA/DNA-binding proteins. Psi achieves growth control through interaction with Mediator, observations that should put to rest controversy surrounding Pol II transcriptional functions for these KH domain proteins.

AB - Drosophila genetic studies demonstrate that cell and tissue growth regulation is a primary developmental function of P-element somatic inhibitor (Psi), the sole ortholog of FUBP family RNA/DNA-binding proteins. Psi achieves growth control through interaction with Mediator, observations that should put to rest controversy surrounding Pol II transcriptional functions for these KH domain proteins.

KW - Drosophila

KW - FUBP1

KW - Growth control

KW - MYC

KW - Psi

UR - http://www.scopus.com/inward/record.url?scp=85021418165&partnerID=8YFLogxK

U2 - 10.1080/21541264.2017.1293595

DO - 10.1080/21541264.2017.1293595

M3 - Review article

SN - 2154-1264

VL - 8

SP - 185

EP - 192

JO - Transcription

JF - Transcription

IS - 3

ER -

FUBP/KH domain proteins in transcription: Back to the future

Abstract

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