Abstract
Metallic nanoparticles such as magnetic (iron, manganese, cobalt, chromium, and nickel), gold, silver, and transition element-based nanoparticles have been extensively studied for the development of new generation cancer therapeutic and diagnostic tools. These metallic nanoparticles are easy to synthesize, surface functionalize, and also possess unique physical and chemical properties which are suitable for theranostic applications. The role of metallic nanoparticles as nanoimaging (fluorescence imaging, magnetic resonance imaging) has been potentially used in detection and diagnosis of cancer at early stage. A multifunctional targeted drug delivery using intrinsic stimuli-responsive (pH, thermal) or extrinsic such as light, heat, and ultrasound has endowed a huge nanoplatform for their therapeutic potential for simultaneous detection (diagnostic) and treatment (therapeutic) of cancer. Moreover, the new development of theranostic hybrid multifunctional nanocarriers has greatly expanded their application in nanomedicines through combining the suitable imaging modalities agents with chemotherapeutic drugs to treat cancer with better, more precise, and minimally invasive approaches. This chapter provides the basic characteristics of multifunctional metallic nanoparticles and their nanotechnological application in theranostics. Finally, we will highlight the future perspective of multifunctional metallic nanoparticles in clinical and nanotechnological cancer research.
| Original language | English |
|---|---|
| Title of host publication | Multifunctional And Targeted Theranostic Nanomedicines |
| Subtitle of host publication | Formulation, Design And Applications |
| Publisher | Springer Nature |
| Pages | 97-117 |
| Number of pages | 21 |
| ISBN (Electronic) | 9789819905386 |
| ISBN (Print) | 9789819905379 |
| DOIs | |
| Publication status | Published - 23 Aug 2023 |
| Externally published | Yes |