Generation of Pseudocontact Shifts in Proteins with Lanthanides Using Small "Clickable" Nitrilotriacetic Acid and Iminodiacetic Acid Tags

Choy Loh; Bim Graham; Elwy Abdelkader Ali; Kellie L Tuck; Gottfried Otting

doi:10.1002/chem.201406274

Generation of Pseudocontact Shifts in Proteins with Lanthanides Using Small "Clickable" Nitrilotriacetic Acid and Iminodiacetic Acid Tags

Choy Loh, Bim Graham, Elwy Abdelkader Ali, Kellie L Tuck, Gottfried Otting

Research output: Contribution to journal › Article › peer-review

Abstract

Pseudocontact shifts (PCS) induced by paramagnetic lanthanide ions provide unique long-range structural information in nuclear magnetic resonance (NMR) spectra, but the site-specific attachment of lanthanide tags to proteins remains a challenge. Here we i

Original language	English
Pages (from-to)	5084-5092
Journal	Chemistry, A European Journal
Volume	21
Issue number	13
DOIs	https://doi.org/10.1002/chem.201406274
Publication status	Published - 2015

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10.1002/chem.201406274

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author = "Choy Loh and Bim Graham and {Abdelkader Ali}, Elwy and Tuck, {Kellie L} and Gottfried Otting",

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AU - Abdelkader Ali, Elwy

AU - Tuck, Kellie L

AU - Otting, Gottfried

PY - 2015

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DO - 10.1002/chem.201406274

M3 - Article

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SP - 5084

EP - 5092

JO - Chemistry, A European Journal

JF - Chemistry, A European Journal

IS - 13

ER -

Generation of Pseudocontact Shifts in Proteins with Lanthanides Using Small "Clickable" Nitrilotriacetic Acid and Iminodiacetic Acid Tags

Abstract

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