Genetic analysis of four porcine avian influenza viruses isolated from Shandong, China

W. F. Shi*, M. J. Gibbs, Y. Z. Zhang, Z. Zhang, X. M. Zhao, X. Jin, C. D. Zhu, M. F. Yang, N. N. Yang, Y. J. Cui, L. Ji

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    48 Citations (Scopus)

    Abstract

    A Bayesian phylogenetic analysis of eight separate gene segments indicated A/Swine/Shandong/2/2003 (H5N1), A/Swine/Shandong/na/2003 (H9N2), A/Swine/Shandong/nb/2003 (H9N2) and A/Swine/Shandong/nc/2005 (H9N2) probably represent two multiple reassortant lineages, that had not been described before, with genes coming from H5N1, H9N2 and other lineages from poultry in Asia. Amino acid motifs within the haemagglutinin sequence of A/Swine/Shandong/nb/2003 suggested it may be able to infect people, whereas the sequences of the other three isolates suggested they would not have had that capability. Our analysis emphasizes the need for a comprehensive study of the interactions between H5N1 and H9N2 viruses in Asia that includes sequencing and phylogenetic investigation.

    Original languageEnglish
    Pages (from-to)211-217
    Number of pages7
    JournalArchives of Virology
    Volume153
    Issue number1
    DOIs
    Publication statusPublished - Jan 2008

    Fingerprint

    Dive into the research topics of 'Genetic analysis of four porcine avian influenza viruses isolated from Shandong, China'. Together they form a unique fingerprint.

    Cite this