Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology

Qingyun Diao; Liangxian Sun; Huajun Zheng; Zhijiang Zeng; Shengyue Wang; Shufa Xu; Huoqing Zheng; Yanping Chen; Yuanyuan Shi; Yuezhu Wang; Fei Meng; Qingliang Sang; Lianfei Cao; Fang Liu; Yongqiang Zhu; Wenfeng Li; Zhiguo Li; Congjie Dai; Minjun Yang; Shenglu Chen; Runsheng Chen; Shaowu Zhang; Jay D. Evans; Qiang Huang; Jie Liu; Fuliang Hu; Songkun Su; Jie Wu

doi:10.1038/s41598-017-17338-6

Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology

Qingyun Diao, Liangxian Sun, Huajun Zheng, Zhijiang Zeng, Shengyue Wang, Shufa Xu, Huoqing Zheng, Yanping Chen, Yuanyuan Shi, Yuezhu Wang, Fei Meng, Qingliang Sang, Lianfei Cao, Fang Liu, Yongqiang Zhu, Wenfeng Li, Zhiguo Li, Congjie Dai, Minjun Yang, Shenglu ChenRunsheng Chen, Shaowu Zhang, Jay D. Evans, Qiang Huang, Jie Liu, Fuliang Hu^*, Songkun Su, Jie Wu

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

43 Citations (Scopus)

Abstract

The Asian honeybee Apis cerana is one of two bee species that have been commercially kept with immense economic value. Here we present the analysis of genomic sequence and transcriptomic exploration for A. cerana as well as the comparative genomic analysis of the Asian honeybee and the European honeybee A. mellifera. The genome and RNA-seq data yield new insights into the behavioral and physiological resistance to the parasitic mite Varroa the evolution of antimicrobial peptides, and the genetic basis for labor division in A. cerana. Comparison of genes between the two sister species revealed genes specific to A. cerana, 54.5% of which have no homology to any known proteins. The observation that A. cerana displayed significantly more vigilant grooming behaviors to the presence of Varroa than A. mellifera in conjunction with gene expression analysis suggests that parasite-defensive grooming in A. cerana is likely triggered not only by exogenous stimuli through visual and olfactory detection of the parasite, but also by genetically endogenous processes that periodically activates a bout of grooming to remove the ectoparasite. This information provides a valuable platform to facilitate the traits unique to A. cerana as well as those shared with other social bees for health improvement.

Original language	English
Article number	822
Journal	Scientific Reports
Volume	8
Issue number	1
DOIs	https://doi.org/10.1038/s41598-017-17338-6
Publication status	Published - 1 Dec 2018

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Diao, Q., Sun, L., Zheng, H., Zeng, Z., Wang, S., Xu, S., Zheng, H., Chen, Y., Shi, Y., Wang, Y., Meng, F., Sang, Q., Cao, L., Liu, F., Zhu, Y., Li, W., Li, Z., Dai, C., Yang, M., ... Wu, J. (2018). Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology. Scientific Reports, 8(1), Article 822. https://doi.org/10.1038/s41598-017-17338-6

@article{82bf71102fce472da89bf0bf4751e3d1,

title = "Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology",

abstract = "The Asian honeybee Apis cerana is one of two bee species that have been commercially kept with immense economic value. Here we present the analysis of genomic sequence and transcriptomic exploration for A. cerana as well as the comparative genomic analysis of the Asian honeybee and the European honeybee A. mellifera. The genome and RNA-seq data yield new insights into the behavioral and physiological resistance to the parasitic mite Varroa the evolution of antimicrobial peptides, and the genetic basis for labor division in A. cerana. Comparison of genes between the two sister species revealed genes specific to A. cerana, 54.5% of which have no homology to any known proteins. The observation that A. cerana displayed significantly more vigilant grooming behaviors to the presence of Varroa than A. mellifera in conjunction with gene expression analysis suggests that parasite-defensive grooming in A. cerana is likely triggered not only by exogenous stimuli through visual and olfactory detection of the parasite, but also by genetically endogenous processes that periodically activates a bout of grooming to remove the ectoparasite. This information provides a valuable platform to facilitate the traits unique to A. cerana as well as those shared with other social bees for health improvement.",

author = "Qingyun Diao and Liangxian Sun and Huajun Zheng and Zhijiang Zeng and Shengyue Wang and Shufa Xu and Huoqing Zheng and Yanping Chen and Yuanyuan Shi and Yuezhu Wang and Fei Meng and Qingliang Sang and Lianfei Cao and Fang Liu and Yongqiang Zhu and Wenfeng Li and Zhiguo Li and Congjie Dai and Minjun Yang and Shenglu Chen and Runsheng Chen and Shaowu Zhang and Evans, {Jay D.} and Qiang Huang and Jie Liu and Fuliang Hu and Songkun Su and Jie Wu",

note = "Publisher Copyright: {\textcopyright} 2018 The Author(s).",

year = "2018",

month = dec,

day = "1",

doi = "10.1038/s41598-017-17338-6",

language = "English",

volume = "8",

journal = "Scientific Reports",

issn = "2045-2322",

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Diao, Q, Sun, L, Zheng, H, Zeng, Z, Wang, S, Xu, S, Zheng, H, Chen, Y, Shi, Y, Wang, Y, Meng, F, Sang, Q, Cao, L, Liu, F, Zhu, Y, Li, W, Li, Z, Dai, C, Yang, M, Chen, S, Chen, R, Zhang, S, Evans, JD, Huang, Q, Liu, J, Hu, F, Su, S & Wu, J 2018, 'Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology', Scientific Reports, vol. 8, no. 1, 822. https://doi.org/10.1038/s41598-017-17338-6

TY - JOUR

T1 - Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology

AU - Diao, Qingyun

AU - Sun, Liangxian

AU - Zheng, Huajun

AU - Zeng, Zhijiang

AU - Wang, Shengyue

AU - Xu, Shufa

AU - Zheng, Huoqing

AU - Chen, Yanping

AU - Shi, Yuanyuan

AU - Wang, Yuezhu

AU - Meng, Fei

AU - Sang, Qingliang

AU - Cao, Lianfei

AU - Liu, Fang

AU - Zhu, Yongqiang

AU - Li, Wenfeng

AU - Li, Zhiguo

AU - Dai, Congjie

AU - Yang, Minjun

AU - Chen, Shenglu

AU - Chen, Runsheng

AU - Zhang, Shaowu

AU - Evans, Jay D.

AU - Huang, Qiang

AU - Liu, Jie

AU - Hu, Fuliang

AU - Su, Songkun

AU - Wu, Jie

PY - 2018/12/1

Y1 - 2018/12/1

N2 - The Asian honeybee Apis cerana is one of two bee species that have been commercially kept with immense economic value. Here we present the analysis of genomic sequence and transcriptomic exploration for A. cerana as well as the comparative genomic analysis of the Asian honeybee and the European honeybee A. mellifera. The genome and RNA-seq data yield new insights into the behavioral and physiological resistance to the parasitic mite Varroa the evolution of antimicrobial peptides, and the genetic basis for labor division in A. cerana. Comparison of genes between the two sister species revealed genes specific to A. cerana, 54.5% of which have no homology to any known proteins. The observation that A. cerana displayed significantly more vigilant grooming behaviors to the presence of Varroa than A. mellifera in conjunction with gene expression analysis suggests that parasite-defensive grooming in A. cerana is likely triggered not only by exogenous stimuli through visual and olfactory detection of the parasite, but also by genetically endogenous processes that periodically activates a bout of grooming to remove the ectoparasite. This information provides a valuable platform to facilitate the traits unique to A. cerana as well as those shared with other social bees for health improvement.

AB - The Asian honeybee Apis cerana is one of two bee species that have been commercially kept with immense economic value. Here we present the analysis of genomic sequence and transcriptomic exploration for A. cerana as well as the comparative genomic analysis of the Asian honeybee and the European honeybee A. mellifera. The genome and RNA-seq data yield new insights into the behavioral and physiological resistance to the parasitic mite Varroa the evolution of antimicrobial peptides, and the genetic basis for labor division in A. cerana. Comparison of genes between the two sister species revealed genes specific to A. cerana, 54.5% of which have no homology to any known proteins. The observation that A. cerana displayed significantly more vigilant grooming behaviors to the presence of Varroa than A. mellifera in conjunction with gene expression analysis suggests that parasite-defensive grooming in A. cerana is likely triggered not only by exogenous stimuli through visual and olfactory detection of the parasite, but also by genetically endogenous processes that periodically activates a bout of grooming to remove the ectoparasite. This information provides a valuable platform to facilitate the traits unique to A. cerana as well as those shared with other social bees for health improvement.

UR - http://www.scopus.com/inward/record.url?scp=85040815515&partnerID=8YFLogxK

U2 - 10.1038/s41598-017-17338-6

DO - 10.1038/s41598-017-17338-6

M3 - Article

SN - 2045-2322

VL - 8

JO - Scientific Reports

JF - Scientific Reports

IS - 1

M1 - 822

ER -

Genomic and transcriptomic analysis of the Asian honeybee Apis cerana provides novel insights into honeybee biology

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