Gold nanotip array for ultrasensitive electrochemical sensing and spectroscopic monitoring

Yueyue Jiang; Fanben Meng; Dianpeng Qi; Pingqiang Cai; Zongyou Yin; Fangwei Shao; Hua Zhang; Freddy Boey; Xiaodong Chen

doi:10.1002/smll.201202620

Gold nanotip array for ultrasensitive electrochemical sensing and spectroscopic monitoring

Yueyue Jiang, Fanben Meng, Dianpeng Qi, Pingqiang Cai, Zongyou Yin, Fangwei Shao, Hua Zhang, Freddy Boey, Xiaodong Chen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

24 Citations (Scopus)

Abstract

A gold nanotip array platform with a combination of ultrasensitive electrochemical sensing and spectroscopic monitoring capability is reported. Adenosine triphosphate is detected down to 1 pM according to the impedance changes in response to aptamer-specific binding. Furthermore, the local molecular information can be monitored at the individual plasmonic nanotips, and hence provide the capability for a better understanding of complex biological processes.

Original language	English
Pages (from-to)	2260-2265
Number of pages	6
Journal	Small
Volume	9
Issue number	13
DOIs	https://doi.org/10.1002/smll.201202620
Publication status	Published - 8 Jul 2013
Externally published	Yes

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10.1002/smll.201202620

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AU - Jiang, Yueyue

AU - Meng, Fanben

AU - Qi, Dianpeng

AU - Cai, Pingqiang

AU - Yin, Zongyou

AU - Shao, Fangwei

AU - Zhang, Hua

AU - Boey, Freddy

AU - Chen, Xiaodong

PY - 2013/7/8

Y1 - 2013/7/8

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AB - A gold nanotip array platform with a combination of ultrasensitive electrochemical sensing and spectroscopic monitoring capability is reported. Adenosine triphosphate is detected down to 1 pM according to the impedance changes in response to aptamer-specific binding. Furthermore, the local molecular information can be monitored at the individual plasmonic nanotips, and hence provide the capability for a better understanding of complex biological processes.

KW - adenosine triphosphate

KW - nanotip arrays

KW - raman scattering

KW - redox electrochemistry

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U2 - 10.1002/smll.201202620

DO - 10.1002/smll.201202620

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SN - 1613-6810

VL - 9

SP - 2260

EP - 2265

JO - Small

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IS - 13

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Gold nanotip array for ultrasensitive electrochemical sensing and spectroscopic monitoring

Abstract

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