Hierarchical sparse brain network estimation

Abd Krim Seghouane*, Muhammad Usman Khalid

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    6 Citations (Scopus)

    Abstract

    Brain networks explore the dependence relationships between brain regions under consideration through the estimation of the precision matrix. An approach based on linear regression is adopted here for estimating the partial correlation matrix from functional brain imaging data. Knowing that brain networks are sparse and hierarchical, the l1-norm penalized regression has been used to estimate sparse brain networks. Although capable of including the sparsity information, the l1-norm penalty alone doesn't incorporate the hierarchical structure prior information when estimating brain networks. In this paper, a new l1 regularization method that applies the sparsity constraint at hierarchical levels is proposed and its implementation described. This hierarchical sparsity approach has the advantage of generating brain networks that are sparse at all levels of the hierarchy. The performance of the proposed approach in comparison to other existing methods is illustrated on real fMRI data.

    Original languageEnglish
    Title of host publication2012 IEEE International Workshop on Machine Learning for Signal Processing - Proceedings of MLSP 2012
    DOIs
    Publication statusPublished - 2012
    Event2012 22nd IEEE International Workshop on Machine Learning for Signal Processing, MLSP 2012 - Santander, Spain
    Duration: 23 Sept 201226 Sept 2012

    Publication series

    NameIEEE International Workshop on Machine Learning for Signal Processing, MLSP
    ISSN (Print)2161-0363
    ISSN (Electronic)2161-0371

    Conference

    Conference2012 22nd IEEE International Workshop on Machine Learning for Signal Processing, MLSP 2012
    Country/TerritorySpain
    CitySantander
    Period23/09/1226/09/12

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