High burden of RSV hospitalization in very young children: a data linkage study

N. Homaira, J. -L. Oei, K-A. Mallitt, M. E. Abdel-Latif, L. Hilder, B. Bajuk, K. Lui, M. Ferson, A. Nurkic, G. M. Chambers, W. Rawlinson, T. Snelling, A. Jaffe

Research output: Contribution to journalArticlepeer-review

Abstract

Linked administrative population data were used to estimate the burden of childhood respiratory syncytial virus (RSV) hospitalization in an Australian cohort aged <5 years. RSV-coded hospitalizations data were extracted for all children aged <5 years born in New South Wales (NSW), Australia between 2001 and 2010. Incidence was calculated as the total number of new episodes of RSV hospitalization divided by the child-years at risk. Mean cost per episode of RSV hospitalization was estimated using public hospital cost weights. The cohort comprised of 870 314 children. The population-based incidence/1000 child-years of RSV hospitalization for children aged <5 years was 4.9 with a rate of 25.6 in children aged <3 months. The incidence of RSV hospitalization (per 1000 child-years) was 11.0 for Indigenous children, 81.5 for children with bronchopulmonary dysplasia (BPD), 10.2 for preterm children with gestational age (GA) 32-36 weeks, 27.0 for children with GA 28-31 weeks, 39.0 for children with GA <28 weeks and 6.7 for term children with low birthweight. RSV hospitalization was associated with an average annual cost of more than AUD 9 million in NSW. RSV was associated with a substantial burden of childhood hospitalization specifically in children aged <3 months and in Indigenous children and children born preterm or with BPD.
Original languageEnglish
Pages (from-to)1612-1621
Number of pages10
JournalEpidemiology and Infection
Volume144
Issue number8
DOIs
Publication statusPublished - Jun 2016

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