HIV Immunogens: Affinity Is Key

Savit Prabhu; Ian A. Cockburn; Carola G. Vinuesa

doi:10.1016/j.immuni.2018.01.002

HIV Immunogens: Affinity Is Key

Savit Prabhu, Ian A. Cockburn, Carola G. Vinuesa^*

^*Corresponding author for this work

Research output: Contribution to journal › Short survey › peer-review

2 Citations (Scopus)

Abstract

Generation of broadly neutralizing antibodies is a key aim of HIV vaccine design, but the precursor B cells are rare. Abbott et al. (2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers. Generation of broadly neutralizing antibodies is a key aim of HIV vaccine design, but the precursor B cells are rare. Abbott et al. (2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers.

Original language	English
Pages (from-to)	11-13
Number of pages	3
Journal	Immunity
Volume	48
Issue number	1
DOIs	https://doi.org/10.1016/j.immuni.2018.01.002
Publication status	Published - 16 Jan 2018

Access to Document

10.1016/j.immuni.2018.01.002

Cite this

@article{7a5320fbf10b4a008f1839291a7e2f44,

title = "HIV Immunogens: Affinity Is Key",

abstract = "Generation of broadly neutralizing antibodies is a key aim of HIV vaccine design, but the precursor B cells are rare. Abbott et al. (2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers. Generation of broadly neutralizing antibodies is a key aim of HIV vaccine design, but the precursor B cells are rare. Abbott et al. (2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers.",

author = "Savit Prabhu and Cockburn, {Ian A.} and Vinuesa, {Carola G.}",

note = "Publisher Copyright: {\textcopyright} 2018",

year = "2018",

month = jan,

day = "16",

doi = "10.1016/j.immuni.2018.01.002",

language = "English",

volume = "48",

pages = "11--13",

journal = "Immunity",

issn = "1074-7613",

publisher = "Cell Press",

number = "1",

}

TY - JOUR

T1 - HIV Immunogens

T2 - Affinity Is Key

AU - Prabhu, Savit

AU - Cockburn, Ian A.

AU - Vinuesa, Carola G.

PY - 2018/1/16

Y1 - 2018/1/16

N2 - Generation of broadly neutralizing antibodies is a key aim of HIV vaccine design, but the precursor B cells are rare. Abbott et al. (2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers. Generation of broadly neutralizing antibodies is a key aim of HIV vaccine design, but the precursor B cells are rare. Abbott et al. (2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers.

AB - Generation of broadly neutralizing antibodies is a key aim of HIV vaccine design, but the precursor B cells are rare. Abbott et al. (2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers. Generation of broadly neutralizing antibodies is a key aim of HIV vaccine design, but the precursor B cells are rare. Abbott et al. (2018) report that high affinity and avidity immunogens are required to promote maturation of low frequency B cells in germinal centers.

UR - http://www.scopus.com/inward/record.url?scp=85044854734&partnerID=8YFLogxK

U2 - 10.1016/j.immuni.2018.01.002

DO - 10.1016/j.immuni.2018.01.002

M3 - Short survey

SN - 1074-7613

VL - 48

SP - 11

EP - 13

JO - Immunity

JF - Immunity

IS - 1

ER -

HIV Immunogens: Affinity Is Key

Abstract

Access to Document

Other files and links

Fingerprint

Cite this