Holographic optical probing of the computing properties of single neurons

Vincent Daria*

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review


    Neurons receive synaptic inputs via its dendrites and understanding the processing of those inputs as well as the influence of the dendrite's non-linear properties are key components to decode the neuron's computing power. Recent breakthroughs to understand dendritic function make use holographic structured illumination to stimulate and/or record dendritic activity either via photochemical or optogenetic tools. In this talk, I will summarize our efforts where we used holograms to probe the integrative and non-linear properties of dendrites of a neuron. Understanding the role of dendrites in neuronal function offer significant insights as to how these neurons function as tiny computers in the brain.

    Original languageEnglish
    Title of host publicationBiomedical Imaging and Sensing Conference 2021
    EditorsToyohiko Yatagai, Yoshihisa Aizu, Osamu Matoba, Yasuhiro Awatsuji, Yuan Luo
    ISBN (Electronic)9781510647190
    Publication statusPublished - 2021
    EventBiomedical Imaging and Sensing Conference 2021 - Virtual, Online, Japan
    Duration: 20 Apr 202122 Apr 2021

    Publication series

    NameProceedings of SPIE - The International Society for Optical Engineering
    ISSN (Print)0277-786X
    ISSN (Electronic)1996-756X


    ConferenceBiomedical Imaging and Sensing Conference 2021
    CityVirtual, Online


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