Human Body to Water Reservoirs: Estimating Viral Population Characteristics Using High-Throughput Sequencing

Duleepa Jayasundara; Sen Lin Tang; Saman K. Halgamuge

doi:10.1016/B978-0-08-102268-9.00007-0

Human Body to Water Reservoirs: Estimating Viral Population Characteristics Using High-Throughput Sequencing

Duleepa Jayasundara^*, Sen Lin Tang, Saman K. Halgamuge

^*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

Abstract

The behavior of bacteria and viruses, as opposed to individual organisms, is key to understanding their impact on biological and ecological systems. Emergence of this concept opened new avenues in the field of microbial genetics, as scientists started looking at the microbial and viral world from the point of view of population genetics.The composition (number, type, and relative abundance of species), functional characteristics, inter- and intraspecies interactions, and evolutionary characteristics of a viral population are topics of highest interest in the field of metagenomics. Current research findings support the importance of studying viruses as populations rather than as individuals.Current bioinformatics methods and tools that are developed to infer population characteristics of viral quasispecies populations and environmental viral populations are discussed in this chapter.

Original language	English
Title of host publication	Metagenomics
Subtitle of host publication	Perspectives, Methods, and Applications
Publisher	Elsevier Inc.
Pages	139-155
Number of pages	17
ISBN (Electronic)	9780128134030
ISBN (Print)	9780081022689
DOIs	https://doi.org/10.1016/B978-0-08-102268-9.00007-0
Publication status	Published - 2018

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title = "Human Body to Water Reservoirs: Estimating Viral Population Characteristics Using High-Throughput Sequencing",

abstract = "The behavior of bacteria and viruses, as opposed to individual organisms, is key to understanding their impact on biological and ecological systems. Emergence of this concept opened new avenues in the field of microbial genetics, as scientists started looking at the microbial and viral world from the point of view of population genetics.The composition (number, type, and relative abundance of species), functional characteristics, inter- and intraspecies interactions, and evolutionary characteristics of a viral population are topics of highest interest in the field of metagenomics. Current research findings support the importance of studying viruses as populations rather than as individuals.Current bioinformatics methods and tools that are developed to infer population characteristics of viral quasispecies populations and environmental viral populations are discussed in this chapter.",

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AU - Halgamuge, Saman K.

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AB - The behavior of bacteria and viruses, as opposed to individual organisms, is key to understanding their impact on biological and ecological systems. Emergence of this concept opened new avenues in the field of microbial genetics, as scientists started looking at the microbial and viral world from the point of view of population genetics.The composition (number, type, and relative abundance of species), functional characteristics, inter- and intraspecies interactions, and evolutionary characteristics of a viral population are topics of highest interest in the field of metagenomics. Current research findings support the importance of studying viruses as populations rather than as individuals.Current bioinformatics methods and tools that are developed to infer population characteristics of viral quasispecies populations and environmental viral populations are discussed in this chapter.

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PB - Elsevier Inc.

ER -

Human Body to Water Reservoirs: Estimating Viral Population Characteristics Using High-Throughput Sequencing

Abstract

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