Huntington’s disease: Managing neuropsychiatric symptoms in Huntington’s disease

Samantha M. Loi; Mark Walterfang; Dennis Velakoulis; Jeffrey C.L. Looi

doi:10.1177/1039856218766120

Huntington’s disease: Managing neuropsychiatric symptoms in Huntington’s disease

Samantha M. Loi^*, Mark Walterfang, Dennis Velakoulis, Jeffrey C.L. Looi

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

Abstract

Objectives: This clinical update review focuses on the management of the neuropsychiatric manifestations of Huntington’s disease (HD). The review highlights current issues regarding pharmacological and non-pharmacological treatment, putative therapeutics and recent relevant research findings in this area. Conclusions: Neuropsychiatric symptoms may precede the classic motor clinical symptoms of HD (prodromal HD) by decades and cause significant functional impairment. Early recognition and comprehensive non-pharmacological, usually in combination with pharmacological, treatment is essential.

Original language	English
Pages (from-to)	376-380
Number of pages	5
Journal	Australasian Psychiatry
Volume	26
Issue number	4
DOIs	https://doi.org/10.1177/1039856218766120
Publication status	Published - 1 Aug 2018

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abstract = "Objectives: This clinical update review focuses on the management of the neuropsychiatric manifestations of Huntington{\textquoteright}s disease (HD). The review highlights current issues regarding pharmacological and non-pharmacological treatment, putative therapeutics and recent relevant research findings in this area. Conclusions: Neuropsychiatric symptoms may precede the classic motor clinical symptoms of HD (prodromal HD) by decades and cause significant functional impairment. Early recognition and comprehensive non-pharmacological, usually in combination with pharmacological, treatment is essential.",

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AU - Velakoulis, Dennis

AU - Looi, Jeffrey C.L.

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N2 - Objectives: This clinical update review focuses on the management of the neuropsychiatric manifestations of Huntington’s disease (HD). The review highlights current issues regarding pharmacological and non-pharmacological treatment, putative therapeutics and recent relevant research findings in this area. Conclusions: Neuropsychiatric symptoms may precede the classic motor clinical symptoms of HD (prodromal HD) by decades and cause significant functional impairment. Early recognition and comprehensive non-pharmacological, usually in combination with pharmacological, treatment is essential.

AB - Objectives: This clinical update review focuses on the management of the neuropsychiatric manifestations of Huntington’s disease (HD). The review highlights current issues regarding pharmacological and non-pharmacological treatment, putative therapeutics and recent relevant research findings in this area. Conclusions: Neuropsychiatric symptoms may precede the classic motor clinical symptoms of HD (prodromal HD) by decades and cause significant functional impairment. Early recognition and comprehensive non-pharmacological, usually in combination with pharmacological, treatment is essential.

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Huntington’s disease: Managing neuropsychiatric symptoms in Huntington’s disease

Abstract

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