Abstract
Patients receiving chemotherapy for various malignancies are at risk of immunosuppression, which can lead to infective complications resulting in delayed therapy and potential progression of disease. Newer agents are now available for the management of castrate-resistant, metastatic prostate cancer, which have shown improved outcomes in progression-free survival and overall survival, and are particularly advantageous in elderly patients who would not otherwise tolerate traditional chemotherapy. These agents work on steroidogenesis pathways and do not affect immune function. We describe 3 cases whereby significant septic complications occurred in the setting of abiraterone use that were associated with hypogammaglobulinemia
| Original language | English |
|---|---|
| Pages | online |
| No. | online |
| Specialist publication | Targetedonc.com |
| Publication status | Published - 2016 |