Improved robust performance in a system for automatic administration of a vasoactive drug

Nicolò Malagutti*, Arvin Dehghani, Rodney A. Kennedy

*Corresponding author for this work

    Research output: Chapter in Book/Report/Conference proceedingConference contributionpeer-review

    4 Citations (Scopus)

    Abstract

    The problem of automatic administration of vasoactive drugs to regulate mean arterial pressure in surgical and postsurgical patients can be considered as a setpoint tracking problem involving a system which is characterised by significant modelling uncertainty in the form of uncertain parameters, unmodelled dynamics and disturbances. Yet, specific levels of performance are required and patient safety must be guaranteed. As part of the development process of a novel Multiple-Model Adaptive Control (MMAC) architecture for this application, we have adopted a mixed-μ synthesis approach to controller design. Simulation results show that the new controllers are capable of improved disturbance rejection and robustness even in the face of large system delays and parametric uncertainty.

    Original languageEnglish
    Title of host publicationBIOSIGNALS 2012 - Proceedings of the International Conference on Bio-inspired Systems and Signal Processing
    Pages282-290
    Number of pages9
    Publication statusPublished - 2012
    EventInternational Conference on Bio-inspired Systems and Signal Processing, BIOSIGNALS 2012 - Vilamoura, Algarve, Portugal
    Duration: 1 Feb 20124 Feb 2012

    Publication series

    NameBIOSIGNALS 2012 - Proceedings of the International Conference on Bio-Inspired Systems and Signal Processing

    Conference

    ConferenceInternational Conference on Bio-inspired Systems and Signal Processing, BIOSIGNALS 2012
    Country/TerritoryPortugal
    CityVilamoura, Algarve
    Period1/02/124/02/12

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