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Influences of Porosity on the In-Vitro Cell Responses of Cold Sprayed Ti-Ta Composites

  • Guang Zeng*
  • , Saden H. Zahiri
  • , Stefan Gulizia
  • , Xiao Bo Chen
  • , Ivan Cole
  • *Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceeding › Conference Paper › peer-review

Abstract

Surface topography as one of the most influential factors in determining the complex processes of cell responses in tissue engineering has been widely investigated. This study explores contributions of pososity upon cold sprayed Ti-Ta composite to cell responses. In-vitro cell culture was firstly discussed the interaction of cells to the polished counterparts with a moderate porosity and with low porosity of Ti-Ta composites, respectively. The significantly enhanced cell growth rate on the polished surface of Ti-Ta composite with moderate porosity compared to the polished surfaces with low porosity was observed during the initial cell culture period (0.5 h; 1 h; 3 h and 6 h). This research indicates cold spray manufacturing could be utilized to produce porous structures with benefits to enhance the osseointegration for biomedical applications.

Original languageEnglish
Title of host publicationProceedings of the 2nd International Conference on Advanced Surface Enhancement, INCASE 2021 - Innovation Leading to Industrialization
EditorsYuefan Wei, Shuyun Chng
PublisherSpringer Science+Business Media B.V.
Pages181-184
Number of pages4
ISBN (Print)9789811657627
DOIs
Publication statusPublished - 2022
Externally publishedYes
Event2nd International Conference on Advanced Surface Enhancement, INCASE 2021 - Virtual, Online
Duration: 7 Sept 2021 → 8 Sept 2021

Publication series

NameLecture Notes in Mechanical Engineering
ISSN (Print)2195-4356
ISSN (Electronic)2195-4364

Conference

Conference2nd International Conference on Advanced Surface Enhancement, INCASE 2021
CityVirtual, Online
Period7/09/21 → 8/09/21

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