Interconnected networks: Structural and dynamic characterization of aqueous dispersions of dioctanoylphosphatidylcholine

Pierandrea Lo Nostro; Sergio Murgia; Marco Lagi; Emiliano Fratini; Göran Karlsson; Mats Almgren; Maura Monduzzi; Barry W. Ninham; Piero Baglioni

doi:10.1021/jp803983t

Interconnected networks: Structural and dynamic characterization of aqueous dispersions of dioctanoylphosphatidylcholine

Pierandrea Lo Nostro^*, Sergio Murgia, Marco Lagi, Emiliano Fratini, Göran Karlsson, Mats Almgren, Maura Monduzzi, Barry W. Ninham, Piero Baglioni

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Aqueous dispersions of the phospholipid dioctanoylphosphatidylcholine (diCsPC) phase-separate below a cloud-point temperature, depending on lipid concentration. The lower phase is viscous and rich in lipid. The structure and dynamics of this system were explored via cryo-transmission electron microscopy (cryo-TEM), small-angle X-ray scattering (SAXS), and NMR. The lower phase comprises a highly interconnected tridimensional network of wormlike micelles. A molecular mechanism for the phase separation is suggested.

Original language	English
Pages (from-to)	12625-12634
Number of pages	10
Journal	Journal of Physical Chemistry B
Volume	112
Issue number	40
DOIs	https://doi.org/10.1021/jp803983t
Publication status	Published - 9 Oct 2008

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title = "Interconnected networks: Structural and dynamic characterization of aqueous dispersions of dioctanoylphosphatidylcholine",

abstract = "Aqueous dispersions of the phospholipid dioctanoylphosphatidylcholine (diCsPC) phase-separate below a cloud-point temperature, depending on lipid concentration. The lower phase is viscous and rich in lipid. The structure and dynamics of this system were explored via cryo-transmission electron microscopy (cryo-TEM), small-angle X-ray scattering (SAXS), and NMR. The lower phase comprises a highly interconnected tridimensional network of wormlike micelles. A molecular mechanism for the phase separation is suggested.",

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T1 - Interconnected networks

T2 - Structural and dynamic characterization of aqueous dispersions of dioctanoylphosphatidylcholine

AU - Lo Nostro, Pierandrea

AU - Murgia, Sergio

AU - Lagi, Marco

AU - Fratini, Emiliano

AU - Karlsson, Göran

AU - Almgren, Mats

AU - Monduzzi, Maura

AU - Ninham, Barry W.

AU - Baglioni, Piero

PY - 2008/10/9

Y1 - 2008/10/9

N2 - Aqueous dispersions of the phospholipid dioctanoylphosphatidylcholine (diCsPC) phase-separate below a cloud-point temperature, depending on lipid concentration. The lower phase is viscous and rich in lipid. The structure and dynamics of this system were explored via cryo-transmission electron microscopy (cryo-TEM), small-angle X-ray scattering (SAXS), and NMR. The lower phase comprises a highly interconnected tridimensional network of wormlike micelles. A molecular mechanism for the phase separation is suggested.

AB - Aqueous dispersions of the phospholipid dioctanoylphosphatidylcholine (diCsPC) phase-separate below a cloud-point temperature, depending on lipid concentration. The lower phase is viscous and rich in lipid. The structure and dynamics of this system were explored via cryo-transmission electron microscopy (cryo-TEM), small-angle X-ray scattering (SAXS), and NMR. The lower phase comprises a highly interconnected tridimensional network of wormlike micelles. A molecular mechanism for the phase separation is suggested.

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U2 - 10.1021/jp803983t

DO - 10.1021/jp803983t

M3 - Article

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SP - 12625

EP - 12634

JO - Journal of Physical Chemistry B

JF - Journal of Physical Chemistry B

IS - 40

ER -

Interconnected networks: Structural and dynamic characterization of aqueous dispersions of dioctanoylphosphatidylcholine

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