Isochromophilone IX, a novel GABA-containing metabolite isolated from a cultured fungus, Penicillium sp.

Adam P. Michael, Emily J. Grace, Mike Kotiw, Russell A. Barrow*

*Corresponding author for this work

    Research output: Contribution to journalArticlepeer-review

    31 Citations (Scopus)

    Abstract

    Isochromophilone IX, a novel antibiotic active component was isolated from a penicillium species and investigated. Isochromophilone IX displays a specific rotation with the same sign as isochromophilone VI. It was found that isochromophilone represents the first occurrence of an γ-amino butyric acid (GABA) containing metabolite among only four naturally occuring members of this structure class.

    Original languageEnglish
    Pages (from-to)13-15
    Number of pages3
    JournalAustralian Journal of Chemistry
    Volume56
    Issue number1
    DOIs
    Publication statusPublished - 2003

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