Lactate transportation is required for lymphocyte activation

Stefan Bröer

doi:10.1038/nchembio1205-356

Lactate transportation is required for lymphocyte activation

Stefan Bröer^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Identification of the monocarboxylate transporter 1 as a target of a new class of immunosuppressants shows that aerobic glycolysis and lactate release are essential for the proliferation of activated lymphocytes.

Original language	English
Pages (from-to)	356-357
Number of pages	2
Journal	Nature Chemical Biology
Volume	1
Issue number	7
DOIs	https://doi.org/10.1038/nchembio1205-356
Publication status	Published - Dec 2005

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title = "Lactate transportation is required for lymphocyte activation",

abstract = "Identification of the monocarboxylate transporter 1 as a target of a new class of immunosuppressants shows that aerobic glycolysis and lactate release are essential for the proliferation of activated lymphocytes.",

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JO - Nature Chemical Biology

JF - Nature Chemical Biology

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Lactate transportation is required for lymphocyte activation

Abstract

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