TY - JOUR
T1 - LCCL proteins of apicomplexan parasites
AU - Dessens, Johannes T.
AU - Sinden, Robert E.
AU - Claudianos, Charles
PY - 2004/3
Y1 - 2004/3
N2 - The LCCL module is a conserved, autonomous protein-folding domain that has recently been found in several extracellular proteins of apicomplexan parasites including Plasmodium, Toxoplasma, Cryptosporidium and Theileria, identifying a new protein family in the Apicomplexa. The expression and structure of these modular proteins has fostered speculation about the roles of these novel molecules in immune evasion. Here, the current data and literature on the members of this protein family are reviewed, with a discussion on their possible roles in host-parasite interaction.
AB - The LCCL module is a conserved, autonomous protein-folding domain that has recently been found in several extracellular proteins of apicomplexan parasites including Plasmodium, Toxoplasma, Cryptosporidium and Theileria, identifying a new protein family in the Apicomplexa. The expression and structure of these modular proteins has fostered speculation about the roles of these novel molecules in immune evasion. Here, the current data and literature on the members of this protein family are reviewed, with a discussion on their possible roles in host-parasite interaction.
UR - http://www.scopus.com/inward/record.url?scp=1342328129&partnerID=8YFLogxK
U2 - 10.1016/j.pt.2004.01.002
DO - 10.1016/j.pt.2004.01.002
M3 - Short survey
SN - 1471-4922
VL - 20
SP - 102
EP - 108
JO - Trends in Parasitology
JF - Trends in Parasitology
IS - 3
ER -