TY - JOUR
T1 - Linear naphtho-γ-pyrones
T2 - A naturally occurring scaffold of biological importance
AU - Barrow, R. A.
AU - McCulloch, M. W.B.
PY - 2009
Y1 - 2009
N2 - The linear naphtho-γ-pyrone (LNGP) moiety is a naturally occurring scaffold with broad biological activity ranging through antimicrobial, antiviral, insecticidal and anti-estrogenic activity. This review, the first of its kind, surveys the chemical literature in an effort directed toward assembling data that will facilitate the construction of activity profiles associated with this emerging class of compounds. The structural and associated biological information has been presented in tabular format with all structures revealed throughout the document and referencing that will allow the reader to rapidly access the literature pertaining to a specific activity or structural class.
AB - The linear naphtho-γ-pyrone (LNGP) moiety is a naturally occurring scaffold with broad biological activity ranging through antimicrobial, antiviral, insecticidal and anti-estrogenic activity. This review, the first of its kind, surveys the chemical literature in an effort directed toward assembling data that will facilitate the construction of activity profiles associated with this emerging class of compounds. The structural and associated biological information has been presented in tabular format with all structures revealed throughout the document and referencing that will allow the reader to rapidly access the literature pertaining to a specific activity or structural class.
UR - http://www.scopus.com/inward/record.url?scp=65349124125&partnerID=8YFLogxK
U2 - 10.2174/1389557510909030273
DO - 10.2174/1389557510909030273
M3 - Review article
SN - 1389-5575
VL - 9
SP - 273
EP - 292
JO - Mini-Reviews in Medicinal Chemistry
JF - Mini-Reviews in Medicinal Chemistry
IS - 3
ER -